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How to get fromCharlotte to Saint Charlesby plane, bus, train, train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Charlotte to Saint Charles by plane, bus, train, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport, bus

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    2. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    5h 26m
    $156–466

  2. Bus, train

    cheapest
    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    4. Take the train from Chicago OTC to Genevatrain train
    22h 40m
    $96–234

  3. Train

    1. Take the train from Charlotte Amtrak Station to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the train from Chicago OTC to Genevatrain train
    31h 16m
    $412–883

  4. Drive 770.2 mi

    1. Drive from Charlotte to Saint Charlescar car 770.2 mi
    13h 48m
    $141–203

  5. Fly Charlotte Douglas International Airport to Chicago Midway International Airport, train

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    2. Take the train from Chicago OTC to Genevatrain train
    6h 5m
    $101–469

  6. Fly Charlotte Douglas International Airport to South Bend, train

    1. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    2. Take the train from South Bend Airport to Millennium Stationtrain train
    3. Take the train from Chicago OTC to Genevatrain train
    8h 25m
    $145–692

  7. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the train from Charlotte Amtrak Station to High Pointtrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    3. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus
    7h 24m
    $154–529

  8. Bus

    1. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Rosemont CTA Station to Elgin Transportation Center Bay 4bus bus 603
    24h 54m
    $173–339

Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD) flights

Calendar105Weekly Planes
Duration2h 26mAverage Duration
Ticket$69Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Saint Charles.ExpandLaunch map view
  • Distance: 644.9 mi
  • Duration: 5h 26m

What companies run services between Charlotte, NC, USA and Saint Charles, IL, USA?

You can take a train from Charlotte Amtrak Station to Saint Charles via Cary, Chicago Union Station, Clinton & Quincy, Washington & Canal, Chicago OTC, and Geneva in around 31h 16m. Alternatively, you can take a bus from Charlotte Bus Station to Saint Charles via Atlanta Bus Station, Chicago Bus Station, Chicago, Cumberland, Rosemont, Rosemont CTA Station, and Elgin Transportation Center Bay 4 in around 24h 54m.

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