There are 3 ways to get from Charlotte to Sanibel by plane, bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Charlotte Douglas International Airport (CLT) to Ft. Myers (RSW)plane CLT - RSW
3h 54m$152–567Drive 690.2 mi
cheapest- Drive from Charlotte to Sanibelcar 690.2 mi
12h 17m$126–182Bus (Flixbus)
- Take the bus from Charlotte Bus Station to Orlando Bus Stationbus FlixBus 2433
- Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus FlixBus 2421
16h 58m$164–238
Charlotte Douglas International Airport (CLT) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from Charlotte to Sanibel is to drive which costs $120 - $190 and takes 12h 17m.
The fastest way to get from Charlotte to Sanibel is to fly which takes 3h 54m and costs $150 - $600.
No, there is no direct bus from Charlotte station to Sanibel. However, there are services departing from Charlotte Bus Station and arriving at Fort Myers Bus Stop via Orlando Bus Station. The journey, including transfers, takes approximately 16h 58m.
The distance between Charlotte and Sanibel is 639 miles. The road distance is 694.2 miles.
The best way to get from Charlotte to Sanibel without a car is to bus which takes 16h 58m and costs $160 - $240.
It takes approximately 3h 54m to get from Charlotte to Sanibel, including transfers.
Charlotte to Sanibel bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
The best way to get from Charlotte to Sanibel is to fly which takes 3h 54m and costs $150 - $600. Alternatively, you can bus, which costs $160 - $240 and takes 16h 58m.
Charlotte to Sanibel bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Charlotte to Sanibel is 694 miles. It takes approximately 12h 17m to drive from Charlotte to Sanibel.
What companies run services between Charlotte, NC, USA and Sanibel, FL, USA?
American Airlines, Delta, and Southwest Airlines fly from Charlotte Douglas International Airport (CLT) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from Charlotte Bus Station to Sanibel via Orlando Bus Station and Fort Myers Bus Stop in around 16h 58m.
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $95–550
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Charlotte Bus Station to Orlando Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Once daily
- Estimated price
- $75–120
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 5h 10m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
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Booking & Getting There
There are 3726+ hotels available in Sanibel.

