There are 5 ways to get from Charlotte to Siena by plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Charlotte Douglas International Airport (CLT) to Florence Peretola Airport (FLR)plane CLT - FLR
- Take the train from Firenze S.M.N. to Sienatrain
16h 45m€325–622Fly to Bologna Guglielmo Marconi Airport, train
cheapest- Fly from Charlotte Douglas International Airport (CLT) to Bologna Guglielmo Marconi Airport (BLQ)plane CLT - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
16h 47m€323–1,146Fly to Pisa International Airport, train
- Fly from Charlotte Douglas International Airport (CLT) to Pisa International Airport (PSA)plane CLT - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
17h 8m€339–1,231Fly to Fiumicino International Airport, train
- Fly from Charlotte Douglas International Airport (CLT) to Fiumicino International Airport (FCO)plane CLT - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
16h 32m€504–1,802Fly to Perugia Sant'Egidio Airport, bus
- Fly from Charlotte Douglas International Airport (CLT) to Perugia Sant'Egidio Airport (PEG)plane CLT - PEG
- Take the bus from Perugia to Sienabus
36h 26m€432–1,620
Charlotte Douglas International Airport (CLT) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Charlotte to Siena is to fly and train which costs €500 - €1800 and takes 16h 32m.
The fastest way to get from Charlotte to Siena is to fly and train which takes 16h 32m and costs €500 - €1800.
The distance between Charlotte and Siena is 7655 km.
It takes approximately 16h 45m to get from Charlotte to Siena, including transfers.
Siena is 6h ahead of Charlotte. It is currently 4:28 AM in Charlotte and 10:28 AM in Siena.
There are 2516+ hotels available in Siena.
What companies run services between Charlotte, NC, USA and Siena, Italy?
There is no direct connection from Charlotte to Siena. However, you can take the line 5 bus to Charlotte Douglas Airport, walk to Charlotte Douglas International Airport (CLT) airport, fly to Florence Peretola Airport (FLR), walk to Florence Airport (FLR), take the vehicle to Alamanni - Stazione Smn, walk to Firenze S.M.N., then take the train to Siena. Alternatively, you can take the line 5 bus to Charlotte Douglas Airport, walk to Charlotte Douglas International Airport (CLT) airport, fly to Pisa International Airport (PSA), walk to Pisa Aeroporto, take the train to Pisa Centrale, take the train to Empoli, then take the train to Siena.
- Website
- britishairways.com
Flights from Charlotte Douglas International Airport to Florence Peretola Airport via London Heathrow
- Ave. Duration
- 14h 25m
- When
- Every day
- Estimated price
- €360–1,300
Flights from Charlotte Douglas International Airport to Pisa International Airport via London Heathrow
- Ave. Duration
- 12h 32m
- When
- Every day
- Estimated price
- €320–1,200
Flights from Charlotte Douglas International Airport to Bologna Guglielmo Marconi Airport via London Heathrow
- Ave. Duration
- 15h 57m
- When
- Every day
- Estimated price
- €310–1,100
Flights from Charlotte Douglas International Airport to Fiumicino International Airport
- Ave. Duration
- 9h 10m
- When
- Every day
- Estimated price
- €260–950
Flights from Charlotte Douglas International Airport to Fiumicino International Airport via London Heathrow
- Ave. Duration
- 12h 36m
- When
- Thursday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €270–1,000
Flights from Charlotte Douglas International Airport to Perugia Sant'Egidio Airport via London Heathrow
- Ave. Duration
- 32h 23m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €420–1,600
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–9
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- €30–50
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–18
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Perugia to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €8–14
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Getting to Rome from the airport
Read the travel guide





