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How to get fromCharlotte to Syracuseby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

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There are 10 ways to get from Charlotte to Syracuse by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Syracuse Hancock International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Syracuse Hancock International Airport (SYR)plane plane CLT - SYR
    5h 2m
    $153–860

  2. Bus via New York

    cheapest
    1. Take the bus from Charlotte, NC - 3302 Queen City Dr to New York, NY - 201 West x 37th Stbus bus Charlotte
    2. Take the bus from New York to Syracusebus bus Adt N816 / ...
    19h 57m
    $98–271

  3. Bus

    1. Take the bus from Charlotte Bus Station to Newark Penn Stationbus bus Greyhound US0700 / ...
    2. Take the bus from Newark Penn Station to Syracuse Bus Stationbus bus FlixBus 2685 / ...
    18h
    $128–245

  4. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain train Empire Service / ...
    19h 50m
    $277–583

  5. Drive 688.5 mi

    1. Drive from Charlotte to Syracusecar car 688.5 mi
    13h 27m
    $126–182

  6. Fly Charlotte Douglas International Airport to Rochester, train

    1. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    5h 38m
    $181–994

  7. Fly Charlotte Douglas International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    2. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus
    6h 52m
    $149–792

  8. Fly Charlotte Douglas International Airport to Wilkes-Barre/Scranton International Airport, bus

    1. Fly from Charlotte Douglas International Airport (CLT) to Wilkes-Barre/Scranton International Airport (AVP)plane plane CLT - AVP
    2. Take the bus from Scranton to Syracuse Bus Stationbus bus
    6h 37m
    $137–577

  9. Fly Concord to Rochester, train

    1. Fly from Concord (USA) to Rochester (ROC)plane plane USA - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    5h 40m
    $241–784

  10. Train via Albany

    1. Take the train from Charlotte Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain train
    20h 23m
    $267–678

Charlotte to Syracuse by bus

Calendar23Weekly Buses
Duration18hAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Charlotte to Syracuse.ExpandLaunch map view
  • Distance: 623 mi
  • Duration: 5h 2m

What companies run services between Charlotte, NC, USA and Syracuse, NY, USA?

American Airlines, United Airlines, and Delta fly from Charlotte Douglas International Airport (CLT) to Syracuse Hancock International Airport (SYR) every 2 hours. Alternatively, you can take a bus from Charlotte Bus Station to Syracuse Bus Station via Newark Penn Station in around 18h.

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