There are 6 ways to get from Charlottesville to Florence by plane, bus, train, bus (Flixbus, Greyhound), car, train (Amtrak), or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Charlottesville (CHO) to Florence Regional Airport (FLO)plane CHO - FLO
4h 11m$93–382Bus via Raleigh
cheapest- Take the bus from Charlottesville to Richmondbus
- Take the bus from Richmond to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus
10h 16m$57–98Bus, train (Amtrak)
- Take the bus from Charlottesville to Richmond Staples Mill Road Amtrak Stationbus Amtrak Thruway Connecting Service / ...
- Take the train from Richmond Staples Mill Road Amtrak Station to Florence Stationtrain Palmetto / ...
8h 12mDrive 318.3 mi
- Drive from Charlottesville to Florencecar 318.3 mi
6h 9m$59–84Train (Amtrak)
- Take the train from Charlottesville to Alexandriatrain Northeast Regional / ...
- Take the train from Alexandria to Florence Stationtrain Palmetto / ...
10h 38m$277–428Bus
- Take the bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Stationbus Charlottesville / ...
- Take the bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SCbus Nyc
11h 5m
Charlottesville (CHO) to Florence Regional Airport (FLO) flights
Comparing Your Travel Options
The cheapest way to get from Charlottesville to Florence is to drive which costs $55 - $85 and takes 6h 9m.
The fastest way to get from Charlottesville to Florence is to fly which takes 4h 11m and costs $90 - $390.
No, there is no direct bus from Charlottesville station to Florence station. However, there are services departing from Downtown Transit Station and arriving at Florence Bus Station via Charlottesville, Richmond and Raleigh Bus Station. The journey, including transfers, takes approximately 10h 16m.
No, there is no direct train from Charlottesville to Florence station. However, there are services departing from Charlottesville and arriving at Florence Station via Alexandria. The journey, including transfers, takes approximately 10h 38m.
The distance between Charlottesville and Florence is 295 miles. The road distance is 320.2 miles.
The best way to get from Charlottesville to Florence without a car is to bus and train which takes 8h 12m and costs .
It takes approximately 4h 11m to get from Charlottesville to Florence, including transfers.
Charlottesville to Florence bus services, operated by Flixbus USA, depart from Charlottesville station.
Charlottesville to Florence train services, operated by Amtrak, depart from Charlottesville station.
The best way to get from Charlottesville to Florence is to fly which takes 4h 11m and costs $90 - $390. Alternatively, you can bus via Raleigh, which costs $55 - $100 and takes 10h 16m, you could also train, which costs $270 - $430 and takes 10h 38m.
What companies run services between Charlottesville, VA, USA and Florence, SC, USA?
American Airlines flies from Charlottesville (CHO) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Downtown Transit Station to Florence Bus Station via Alderman Rd at Stadium Rd, Charlottesville, Richmond, Richmond, and Raleigh Bus Station in around 10h 16m.
- Website
- aa.com
Flights from Charlottesville to Florence Regional Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $50–330
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Richmond Staples Mill Road Amtrak Station to Florence Station
- Ave. Duration
- 5h 42m
- Frequency
- Twice daily
- Estimated price
- $160–260
- Website
- Amtrak
Train from Charlottesville to Alexandria
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Amtrak
Train from Alexandria to Florence Station
- Ave. Duration
- 7h 29m
- Frequency
- Twice daily
- Estimated price
- $220–340
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Charlottesville to Richmond Staples Mill Road Amtrak Station
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Website
- Amtrak
Bus from Charlottesville Amtrak Station to Richmond Main Street Amtrak Station
- Ave. Duration
- 2h
- Frequency
- 6 times a week
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Charlottesville to Richmond
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a week
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Richmond to Raleigh Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Twice daily
- Estimated price
- $22–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Richmond to Raleigh Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Every 4 hours
- Estimated price
- $24–40
- Website
- Greyhound
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $24–40
- Website
- Greyhound
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SC
- Ave. Duration
- 5h 53m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $50–75
Want to know more about travelling around United States
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Booking & Getting There
Charlottesville to Florence bus services, operated by Flixbus USA, arrive at Richmond station.
Charlottesville to Florence train services, operated by Amtrak, arrive at Alexandria station.
Yes, the driving distance between Charlottesville to Florence is 320 miles. It takes approximately 6h 9m to drive from Charlottesville to Florence.
Book your Charlottesville to Florence train tickets online with Omio.
Book your Charlottesville to Florence bus tickets online with Omio.
There are 47+ hotels available in Florence.