There are 7 ways to get from Charlottesville to Knoxville by plane, train, bus, taxi, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Charlottesville
best- Fly from Charlottesville (CHO) to Mcghee Tyson Airport (TYS)plane CHO - TYS
4h 6m$208–909Drive 362.7 mi
cheapest- Drive from Charlottesville to Knoxvillecar 362.7 mi
6h 4m$67–96Train, bus, taxi, shuttle, drive
- Take the train from Charlottesville to High Pointtrain
- Take the bus from Forsyth Hospital to Boonebus
- Take the taxi from Boone to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Knoxvillecar
13h 24m$388–487Taxi to Shenandoah Valley Regional Airport, fly
- Take the taxi from Charlottesville to Shenandoah Valley Regional Airport (SHD)taxi
- Fly from Shenandoah Valley Regional Airport (SHD) to Mcghee Tyson Airport (TYS)plane SHD - TYS
5h 47m$320–1,042Train to Ronald Reagan Washington National Airport, fly
- Take the train from Charlottesville to Alexandriatrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane DCA - TYS
5h 25m$315–1,461Bus, taxi, shuttle, drive
- Take the bus from Charlottesville Union Station to Roanoke Bus Stopbus
- Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus Swb
- Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus
- Take the taxi from Bristol Exit 5 Park & Ride Lot to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Chilhowee at Holstoncar
14h 2m$297–342Train, bus, shuttle, drive
- Take the train from Charlottesville to High Pointtrain
- Take the bus from Forsyth Hospital to Boonebus
- Take a shuttle bus from Boone to Black Bear Resort
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Knoxvillecar
14h 59m$352–425
Charlottesville (CHO) to Mcghee Tyson Airport (TYS) flights
Comparing Your Travel Options
The cheapest way to get from Charlottesville to Knoxville is to drive which costs $65 - $100 and takes 6h 4m.
The fastest way to get from Charlottesville to Knoxville is to fly which takes 4h 6m and costs $200 - $950.
The distance between Charlottesville and Knoxville is 370 miles. The road distance is 364.8 miles.
It takes approximately 4h 6m to get from Charlottesville to Knoxville, including transfers.
Yes, the driving distance between Charlottesville to Knoxville is 365 miles. It takes approximately 6h 4m to drive from Charlottesville to Knoxville.
There are 324+ hotels available in Knoxville.
What companies run services between Charlottesville, VA, USA and Knoxville, TN, USA?
American Airlines, United Airlines, and Delta fly from Charlottesville (CHO) to Mcghee Tyson Airport (TYS) hourly.
- Website
- aa.com
Flights from Charlottesville to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $120–800
Flights from Charlottesville to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Shenandoah Valley Regional Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $120–800
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $200–1,300
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $210–1,300
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $250–1,400
- Website
- delta.com
Flights from Charlottesville to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $150–850
Flights from Charlottesville to Mcghee Tyson Airport via New York La Guardia
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $290–1,500
- Website
- united.com
Flights from Charlottesville to Mcghee Tyson Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $130–800
Flights from Charlottesville to Mcghee Tyson Airport via Newark
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Charlottesville to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $210–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlottesville to High Point
- Ave. Duration
- 3h 57m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Amtrak
Train from Charlottesville to Alexandria
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- $55–90
- Website
- Amtrak
Train from Charlottesville to High Point
- Ave. Duration
- 3h 57m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Forsyth Hospital to Boone
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–19
- Schedules at
- Sunway Charters
- Passenger
- $13–19
Bus from Forsyth Hospital to Boone
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–19
- Schedules at
- Sunway Charters
- Passenger
- $13–19
- Phone
- +1-423-725-5988
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Shuttle from Boone to Black Bear Resort
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $86
- Website
- Black Bear Resort Shuttle
Shuttle from Black Bear Resort to Hot Springs
- Ave. Duration
- 1h 30m
- Frequency
- On demand
- Estimated price
- $136
- Website
- Black Bear Resort Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charlottesville Union Station to Roanoke Bus Stop
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 540 982 2222
- [email protected]
- Website
- Valley Metro Roanoke
Bus from 3rd St Station Slip D to Exit 118 - Park and Ride
- Ave. Duration
- 55 min
- Frequency
- Every 3 hours
- Estimated price
- $1–4
- Website
- Valley Metro Roanoke
- Phone
- +1-800-827-3490
- [email protected]
- Website
- Virginia Breeze
Bus from Christiansburg to Bristol Exit 5 Park & Ride Lot
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $25–30
- Schedules at
- Virginia Breeze
- Ave. Duration
- 1h 5m
- Estimated price
- $100–180
High Country Taxi
- Phone
- +1 828-414-1492
- Website
- highcountrytaxi.com
Tipsy Taxi
- Phone
- +1 828-719-8477
- Website
- facebook.com
1st Call Taxi
- Phone
- +1 434-906-6670
- Website
- 1stcalltaxi.wordpress.com
Anytime Taxi
- Phone
- +1 434-977-5522
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