There are 6 ways to get from Charlottesville to Knoxville by plane, train, bus, taxi, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Charlottesville
best- Fly from Charlottesville (CHO) to Mcghee Tyson Airport (TYS)plane CHO - TYS
4h 4m$198–809Drive 362.7 mi
cheapest- Drive from Charlottesville to Knoxvillecar 362.7 mi
6h 4m$67–96Train, bus, taxi, shuttle, drive
- Take the train from Charlottesville to Roanoketrain
- Take the bus from Roanoke Amtrak Station to Exit 118 - Park and Ridebus Swb
- Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus
- Take the taxi from Bristol Exit 5 Park & Ride Lot to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Knoxvillecar
12h 12m$305–377Taxi to Shenandoah Valley Regional Airport, fly
- Take the taxi from Charlottesville to Shenandoah Valley Regional Airport (SHD)taxi
- Fly from Shenandoah Valley Regional Airport (SHD) to Mcghee Tyson Airport (TYS)plane SHD - TYS
6h 1m$310–942Train to Ronald Reagan Washington National Airport, fly
- Take the train from Charlottesville to Alexandriatrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane DCA - TYS
5h 19m$255–1,235Bus, taxi, shuttle, drive
- Take the bus from Charlottesville Union Station to Roanoke Bus Stopbus
- Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus Swb
- Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus
- Take the taxi from Bristol Exit 5 Park & Ride Lot to Black Bear Resorttaxi
- Take a shuttle bus from Black Bear Resort to Hot Springs
- Drive from Hot Springs to Chilhowee at Holstoncar
14h 2m$293–342
Charlottesville (CHO) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Charlottesville to Knoxville is to drive which costs $65 - $100 and takes 6h 4m.
The fastest way to get from Charlottesville to Knoxville is to fly which takes 4h 4m and costs $190 - $850.
The distance between Charlottesville and Knoxville is 370 miles. The road distance is 364.8 miles.
It takes approximately 4h 4m to get from Charlottesville to Knoxville, including transfers.
Yes, the driving distance between Charlottesville to Knoxville is 365 miles. It takes approximately 6h 4m to drive from Charlottesville to Knoxville.
There are 316+ hotels available in Knoxville.
What companies run services between Charlottesville, VA, USA and Knoxville, TN, USA?
American Airlines, United Airlines, and Delta fly from Charlottesville (CHO) to Mcghee Tyson Airport (TYS) hourly.
- Website
- aa.com
Flights from Charlottesville to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $110–700
Flights from Shenandoah Valley Regional Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $110–700
Flights from Shenandoah Valley Regional Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $190–950
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 3h 55m
- When
- Thursday and Sunday
- Estimated price
- $190–1,100
Flights from Ronald Reagan Washington National Airport to Mcghee Tyson Airport via Philadelphia
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charlottesville to Roanoke
- Ave. Duration
- 2h 33m
- Frequency
- Twice daily
- Estimated price
- $30–70
- Website
- Amtrak
Train from Charlottesville to Alexandria
- Ave. Duration
- 2h 9m
- Frequency
- 3 times a day
- Estimated price
- $28–65
- Website
- Amtrak
- Phone
- +1 540 982 2222
- [email protected]
- Website
- Valley Metro Roanoke
Bus from Roanoke Amtrak Station to Exit 118 - Park and Ride
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $1–4
- Website
- Valley Metro Roanoke
Bus from 3rd St Station Slip D to Exit 118 - Park and Ride
- Ave. Duration
- 55 min
- Frequency
- Every 3 hours
- Estimated price
- $1–4
- Website
- Valley Metro Roanoke
- Ave. Duration
- 1h
- Estimated price
- $100–180
1st Call Taxi
- Phone
- +1 434-906-6670
- Website
- 1stcalltaxi.wordpress.com
Anytime Taxi
- Phone
- +1 434-977-5522
Want to know more about travelling around United States
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