Rome2Rio

How to get fromCharlottesville to Louisvilleby plane, bus (Greyhound, Amtrak), train, bus, or car

Find Transport to Louisville

See all options

There are 6 ways to get from Charlottesville to Louisville by plane, bus (Greyhound, Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlottesville to Louisville International Airport

    best
    1. Fly from Charlottesville (CHO) to Louisville International Airport (SDF)plane plane CHO - SDF
    5h 17m
    $144–742

  2. Drive  484.5 mi

    cheapest
    1. Drive from Charlottesville to Louisvillecar car 484.5 mi
    8h 20m
    $89–128

  3. Bus

    1. Take the bus from Charlottesville Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville to Louisville, KYbus bus Nashville
    17h 10m
    $126–201

  4. Train, bus (Amtrak)

    1. Take the train from Charlottesville to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    18h 18m
    $356–557

  5. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    6h 27m
    $230–1,194

  6. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 14m
    $157–660

Charlottesville to Louisville by bus

Calendar7Weekly Buses
Duration17h 10mAverage Duration
Ticket$126Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Charlottesville to Louisville.ExpandLaunch map view
  • Distance: 411.7 mi
  • Duration: 5h 17m

What companies run services between Charlottesville, VA, USA and Louisville, KY, USA?

United Airlines, American Airlines, and Delta fly from Charlottesville (CHO) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Downtown Transit Station to Louisville, KY via W Main St at 8th St NW, Charlottesville Union Station, and Nashville in around 17h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There