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How to get fromCharlottesville to Louisville, KYby plane, bus (Greyhound, Amtrak, Flixbus), train, bus, or car

Find Transport to Louisville, KY

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There are 6 ways to get from Charlottesville to Louisville, KY by plane, bus (Greyhound, Amtrak, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlottesville to Louisville International Airport

    best
    1. Fly from Charlottesville (CHO) to Louisville International Airport (SDF)plane plane CHO - SDF
    5h 49m
    $134–692

  2. Drive  485.7 mi

    cheapest
    1. Drive from Charlottesville to Louisville, KYcar car 485.7 mi
    8h 22m
    $89–128

  3. Bus

    1. Take the bus from Charlottesville Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus Greyhound US0105 / ...
    16h 40m
    $112–186

  4. Train, bus

    1. Take the train from Charlottesville to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus Greyhound US0100 / ...
    18h 13m
    $172–398

  5. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisville, KYcar car
    6h 18m
    $126–634

  6. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    6h 57m
    $179–1,017

Charlottesville to Louisville, KY by bus

Calendar7Weekly Buses
Duration16h 40mAverage Duration
Ticket$112Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charlottesville to Louisville, KY.ExpandLaunch map view
  • Distance: 413.9 mi
  • Duration: 5h 49m

What companies run services between Charlottesville, VA, USA and Louisville, KY, USA?

United Airlines, Delta, and American Airlines fly from Charlottesville (CHO) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Downtown Transit Station to Louisville Bus Station via W Main St at 8th St NW, Charlottesville Union Station, and Nashville Bus Station in around 16h 40m.

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