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How to get fromCharlottesville to Saint Charlesby plane, bus (Greyhound, Flixbus), train (Amtrak), car, taxi, or train

Find Transport to Saint Charles

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There are 7 ways to get from Charlottesville to Saint Charles by plane, bus (Greyhound, Flixbus), train (Amtrak), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlottesville

    best
    1. Fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL)plane plane CHO - STL
    5h 50m
    $153–613

  2. Drive  764 mi

    cheapest
    1. Drive from Charlottesville to Saint Charlescar car 764 mi
    13h
    $140–202

  3. Bus

    1. Take the bus from Charlottesville Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus Greyhound US0186 / ...
    21h 44m
    $151–245

  4. Train (Amtrak)

    1. Take the train from Charlottesville to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    28h 13m
    $298–709

  5. Taxi to Shenandoah Valley Regional Airport, fly

    1. Take the taxi from Charlottesville to Shenandoah Valley Regional Airport (SHD)taxi taxi
    2. Fly from Shenandoah Valley Regional Airport (SHD) to Lambert–St. Louis International Airport (STL)plane plane SHD - STL
    7h 53m
    $265–746

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    7h 1m
    $179–523

  7. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from Charlottesville to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    7h 48m
    $161–1,295

Charlottesville (CHO) to Lambert–St. Louis International Airport (STL) flights

Calendar106Weekly Planes
Duration5h 40mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Charlottesville to Saint Charles.ExpandLaunch map view
  • Distance: 674.9 mi
  • Duration: 5h 50m

What companies run services between Charlottesville, VA, USA and Saint Charles, MO, USA?

United Airlines, American Airlines, and Delta fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Downtown Transit Station to Saint Charles via W Main St at 8th St NW, Charlottesville Union Station, Nashville Bus Station, St Louis Bus Station, CIVIC CENTER station, NORTH HANLEY station, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 21h 44m.

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