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How to get fromChattanooga to Mayo Clinicby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Mayo Clinic

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There are 6 ways to get from Chattanooga to Mayo Clinic by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chattanooga Metropolitan Airport to Rochester

    best
    1. Fly from Chattanooga Metropolitan Airport (CHA) to Rochester (RST)plane plane CHA - RST
    7h 38m
    $97–475

  2. Bus

    1. Take the bus from Groome Transportation Chattanooga to Atlanta Airportbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    29h 39m
    $252–400

  3. Bus, train

    1. Take the bus from Groome Transportation Chattanooga to Atlanta Airportbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the train from Carbondale to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    5. Take the bus from St. Paul to Rochesterbus bus
    29h 40m
    $555–850

  4. Drive  886.8 mi

    1. Drive from Chattanooga to Mayo Cliniccar car 886.8 mi
    15h 23m
    $162–234

  5. Fly Chattanooga Metropolitan Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Chattanooga Metropolitan Airport (CHA) to Minneapolis–Saint Paul International Airport (MSP)plane plane CHA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 55m
    $171–625

  6. Drive to Mcghee Tyson Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Drive from Chattanooga to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane TYS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 37m
    $190–729

Chattanooga Metropolitan Airport (CHA) to Rochester (RST) flights

Calendar48Weekly Planes
Duration8h 34mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chattanooga to Mayo Clinic.ExpandLaunch map view
  • Distance: 743.2 mi
  • Duration: 7h 38m

What companies run services between Chattanooga, TN, USA and Mayo Clinic, MN, USA?

American Airlines and Delta fly from Chattanooga Metropolitan Airport (CHA) to Rochester (RST) every 4 hours. Alternatively, you can take a vehicle from Chattanooga to Mayo Clinic via Groome Transportation Chattanooga, Atlanta Airport, Airport Station, Garnett Station, Atlanta Bus Station, Chicago Bus Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 29h 39m.

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