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How to get fromCheektowaga to Knoxvilleby plane, train, bus, car, or bus (Flixbus)

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There are 7 ways to get from Cheektowaga to Knoxville by plane, train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS)plane plane BUF - TYS
    4h 11m
    $252–1,127

  2. Fly to Nashville, drive

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Nashville (BNA)plane plane BUF - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    4h 59m
    $114–503

  3. Train, bus

    1. Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    21h 33m
    $421–618

  4. Drive  684.7 mi

    1. Drive from Cheektowaga to Knoxvillecar car 684.7 mi
    11h 30m
    $121–175

  5. Bus

    1. Take the bus from Buffalo Niagara International Airport to New York Midtownbus bus FlixBus 2686 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    21h 36m
    $249–350

  6. Train, bus via New York

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the bus from New York to Knoxvillebus bus Nyc
    22h 7m
    $299–531

  7. Train, bus #2

    1. Take the train from Buffalo to New York Penn Stationtrain train VIA Rail
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    22h 11m
    $254–441

Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS) flights

Calendar70Weekly Planes
Duration4h 54mAverage Duration
Ticket$197Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cheektowaga to Knoxville.ExpandLaunch map view
  • Distance: 579.5 mi
  • Duration: 4h 11m

What companies run services between Cheektowaga, NY, USA and Knoxville, TN, USA?

Delta, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from Buffalo Niagara International Airport to Knoxville via New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 21h 36m.

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