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How to get fromChesterfield to Louisvilleby bus (Greyhound), car, or plane

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There are 4 ways to get from Chesterfield to Louisville by bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus Greyhound US0185 / ...
    2. Take the bus from Evansville, IN to Louisville, KYbus bus Evansville
    8h 57m
    $64–109

  2. Drive 280.7 mi

    cheapest
    1. Drive from Chesterfield to Louisvillecar car 280.7 mi
    4h 40m
    $52–74

  3. Fly to Louisville International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    6h 51m
    $105–657

  4. Fly to Blue Grass Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 39m
    $197–1,023

Chesterfield to Louisville by bus and train

Calendar7Weekly Services
Duration8h 57mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

Map of how to get from Chesterfield to Louisville.ExpandLaunch map view
  • Distance: 307.5 mi
  • Duration: 8h 57m

What companies run services between Chesterfield, MO, USA and Louisville, KY, USA?

You can take a bus from Chestrfd Parkway @ Wild Horse Creek Sb to Louisville, KY via Delmar Loop Transit Center Eb, DELMAR LOOP station, CIVIC CENTER station, St Louis Bus Station, and Evansville, IN in around 8h 57m. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) hourly.

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