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How to get fromCheyenne to La Crosseby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 9 ways to get from Cheyenne to La Crosse by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Minneapolis–Saint Paul International Airport, train

    best
    1. Fly from Cheyenne Airport (CYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane CYS - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 30m
    $135–586

  2. Bus, train

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Take the train from Denver to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    28h 50m
    $418–921

  3. Bus

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    32h 30m
    $250–426

  4. Drive 851.3 mi

    1. Drive from Cheyenne to La Crossecar car 851.3 mi
    14h 33m
    $156–225

  5. Fly Cheyenne Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from Cheyenne Airport (CYS) to Dane County Regional Airport-Truax Field (MSN)plane plane CYS - MSN
    2. Take the bus from Madison to La Crossebus bus
    10h 10m
    $174–726

  6. Bus to Denver, fly to La Crosse

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to La Crosse (LSE)plane plane DEN - LSE
    8h 42m
    $167–574

  7. Bus to Denver, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Minneapolis–Saint Paul International Airport (MSP)plane plane DEN - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 43m
    $180–504

  8. Bus to Denver, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Dane County Regional Airport-Truax Field (MSN)plane plane DEN - MSN
    3. Take the bus from Madison to La Crossebus bus
    9h 49m
    $260–748

  9. Bus via Billings

    1. Take the bus from Cheyenne, WY to Billings, MTbus bus
    2. Take the bus from Billings to Minneapolisbus bus
    3. Take the bus from Minneapolis to La Crossebus bus
    32h 55m
    $372–501

Cheyenne to La Crosse by bus

Calendar7Weekly Buses
Duration32h 30mAverage Duration
Ticket$250Cheapest Price
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Questions & Answers

Map of how to get from Cheyenne to La Crosse.ExpandLaunch map view
  • Distance: 777.3 mi
  • Duration: 8h 30m

What companies run services between Cheyenne, WY, USA and La Crosse, WI, USA?

You can take a bus from Cheyenne Regional Medical Center to La Crosse via Cheyenne, Denver Union Station, Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 32h 30m.

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