Rome2Rio

How to get fromCheyenne to La Crosseby plane, train, bus, bus (Greyhound), or car

Find Transport to La Crosse

See all options

There are 8 ways to get from Cheyenne to La Crosse by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Minneapolis–Saint Paul International Airport, train

    best
    1. Fly from Cheyenne Airport (CYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane CYS - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    10h 3m
    $168–610

  2. Drive  851.3 mi

    cheapest
    1. Drive from Cheyenne to La Crossecar car 851.3 mi
    14h 33m
    $156–225

  3. Bus, train

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the train from Denver to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    27h 36m
    $733–1,185

  4. Bus

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to La Crossebus bus
    28h 15m
    $222–335

  5. Fly Cheyenne Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from Cheyenne Airport (CYS) to Dane County Regional Airport-Truax Field (MSN)plane plane CYS - MSN
    2. Take the bus from Madison to La Crossebus bus
    10h 15m
    $163–682

  6. Bus to Denver, fly to Minneapolis–Saint Paul International Airport, train

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Minneapolis–Saint Paul International Airport (MSP)plane plane DEN - MSP
    3. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    9h 43m
    $215–534

  7. Bus to Denver, fly to Dane County Regional Airport-Truax Field, bus

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Dane County Regional Airport-Truax Field (MSN)plane plane DEN - MSN
    3. Take the bus from Madison to La Crossebus bus
    9h 50m
    $200–748

  8. Bus via Billings

    1. Take the bus from Cheyenne to Billingsbus bus
    2. Take the bus from Billings to Minneapolisbus bus
    3. Take the bus from Minneapolis to La Crossebus bus
    32h 55m
    $372–501

Cheyenne to La Crosse by bus

Calendar7Weekly Buses
Duration28h 15mAverage Duration
Ticket$222Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Cheyenne to La Crosse.ExpandLaunch map view
  • Distance: 777.3 mi
  • Duration: 10h 3m

What companies run services between Cheyenne, WY, USA and La Crosse, WI, USA?

You can take a bus from Cheyenne Regional Medical Center to La Crosse via Cheyenne, Denver Union Station, Des Moines, and Minneapolis in around 28h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There