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How to get fromCheyenne to Mayo Clinicby plane, bus, bus (Greyhound), train, car, or taxi

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There are 9 ways to get from Cheyenne to Mayo Clinic by plane, bus, bus (Greyhound), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cheyenne Airport to Minneapolis–Saint Paul International Airport, bus

    best
    1. Fly from Cheyenne Airport (CYS) to Minneapolis–Saint Paul International Airport (MSP)plane plane CYS - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h
    $148–559

  2. Fly Cheyenne Airport to Rochester

    cheapest
    1. Fly from Cheyenne Airport (CYS) to Rochester (RST)plane plane CYS - RST
    9h 7m
    $83–465

  3. Bus

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Des Moinesbus bus
    3. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    4. Take the bus from St. Paul to Rochesterbus bus
    24h 59m
    $211–327

  4. Bus, train

    1. Take the bus from Cheyenne to Denver Union Stationbus bus
    2. Take the train from Denver to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    30h 47m
    $399–807

  5. Drive  789 mi

    1. Drive from Cheyenne to Mayo Cliniccar car 789 mi
    13h 32m
    $144–208

  6. Taxi to Laramie Regional Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the taxi from Cheyenne to Laramie-Airport-LARtaxi taxi
    2. Fly from Laramie Regional Airport (LAR) to Minneapolis–Saint Paul International Airport (MSP)plane plane LAR - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 58m
    $247–720

  7. Bus to Denver, fly to Rochester

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Rochester (RST)plane plane DEN - RST
    8h 36m
    $124–521

  8. Bus to Denver, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Warren AFB to Denver International Airport Pickupsbus bus
    2. Fly from Denver (DEN) to Minneapolis–Saint Paul International Airport (MSP)plane plane DEN - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 8m
    $195–473

  9. Bus via Billings

    1. Take the bus from Cheyenne, WY to Billings, MTbus bus
    2. Take the bus from Billings to Minneapolisbus bus
    3. Take the bus from Minneapolis to Rochesterbus bus
    29h 18m
    $357–481

Cheyenne to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration24h 59mAverage Duration
Ticket$211Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cheyenne to Mayo Clinic.ExpandLaunch map view
  • Distance: 719.4 mi
  • Duration: 7h

What companies run services between Cheyenne, WY, USA and Mayo Clinic, MN, USA?

You can take a bus from Cheyenne to Mayo Clinic via Denver Union Station, Des Moines, St. Paul, and Rochester in around 24h 59m. Alternatively, United Airlines, Delta, and American Airlines fly from Cheyenne Airport (CYS) to Rochester (RST) every 4 hours.

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