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How to get fromChicago Bus Station to Charlotteby plane, bus, train (Amtrak), car, subway, train, or bus (Amtrak, Greyhound)

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There are 8 ways to get from Chicago Bus Station to Charlotte by plane, bus, train (Amtrak), car, subway, train, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    4h 39m
    $128–313

  2. Bus

    cheapest
    1. Take the bus from Chicago to Columbusbus bus Bsb 22 / ...
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    18h 50m
    $77–175

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    28h 33m
    $686–1,054

  4. Drive  728.8 mi

    1. Drive from Chicago Bus Station to Charlottecar car 728.8 mi
    13h 28m
    $133–193

  5. Subway to Chicago Midway International Airport, fly

    1. Take the subway from Quincy to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    4h 26m
    $126–708

  6. Train to South Bend, fly

    1. Take the train from Van Buren St. to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Charlotte Douglas International Airport (CLT)plane plane SBN - CLT
    6h 4m
    $108–569

  7. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    5h 57m
    $192–889

  8. Bus via Toledo

    1. Take the bus from Chicago Union Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus Greyhound US0140
    19h 42m

Chicago Bus Station to Charlotte by bus

Calendar7Weekly Buses
Duration18h 50mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago Bus Station to Charlotte.ExpandLaunch map view
  • Distance: 625.2 mi
  • Duration: 4h 39m

What companies run services between Chicago Bus Station, IL, USA and Charlotte, NC, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT) hourly. Alternatively, you can take a bus from Chicago to Charlotte via Columbus in around 18h 50m.

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