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How to get fromChicago Bus Station to Indianapolisby bus (Flixbus, Greyhound), train (Amtrak), car, subway, or plane

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There are 5 ways to get from Chicago Bus Station to Indianapolis by bus (Flixbus, Greyhound), train (Amtrak), car, subway, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

    •  – 

      bus bus 4h 10m • Direct

    •  – 

      bus bus 4h 2m • 1 change

    •  – 

      bus bus 3h 30m • Direct

  1. Train (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    5h 3m
    $100–170
  2. Drive  179.2 mi

    1. Drive from Chicago Bus Station to Indianapoliscar car 179.2 mi
    3h 12m
    $30–43
  3. Subway to Chicago O'Hare International Airport, fly

    1. Take the subway from Clinton-Blue to Jefferson Parksubway subway
    2. Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane plane ORD - IND
    4h 10m
    $386–812
  4. Subway to Chicago Midway International Airport, fly

    1. Take the subway from Quincy to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane plane MDW - IND
    4h 3m
    $84–607

Chicago Bus Station to Indianapolis by bus

Calendar77Weekly Buses
Duration3h 45mAverage Duration
Ticket$29Cheapest Price
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Comparing Your Travel Options

What companies run services between Chicago Bus Station, IL, USA and Indianapolis, IN, USA?

Flixbus USA operates a bus from Chicago Bus Station to Indianapolis every 4 hours. Tickets cost $29–45 and the journey takes 3h 45m. Greyhound USA also services this route 5 times a day. Alternatively, Amtrak operates a train from Chicago Union Station to Indianapolis 3 times a week. Tickets cost $100–170 and the journey takes 4h 54m.

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Need to know: Greyhound

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