There are 6 ways to get from Chicago Loop to Charleston by subway, plane, train (Amtrak), bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Charleston International Airport
best- Take the subway from Clark/Lake to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane MDW - CHS
5h 16m$114–607Fly Chicago O'Hare International Airport to Columbia, drive
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane ORD - CAE
- Drive from Columbia-Airport-CAE to Charlestoncar
5h 37m$82–365Train (Amtrak)
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain Floridian
- Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain Silver Meteor / ...
28h 39m$732–1,120Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus Greyhound US0100
- Take the bus from Atlanta Bus Station to Charleston Bus Stationbus Greyhound US0641S
30h 12m$195–321Drive 872.8 mi
- Drive from Chicago Loop to Charlestoncar 872.8 mi
16h$160–231Fly Chicago O'Hare International Airport to Charleston International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane ORD - CHS
5h 31m$504–857
Chicago Loop to Charleston by bus
Comparing Your Travel Options
The cheapest way to get from Chicago Loop to Charleston is to drive which costs $150 - $230 and takes 16h.
The fastest way to get from Chicago Loop to Charleston is to subway and fly which takes 5h 16m and costs $110 - $650.
No, there is no direct bus from Chicago Loop station to Charleston. However, there are services departing from Chicago Bus Station and arriving at Transit Mall via Atlanta Bus Station, North Charleston Transit Center and Rivers Ave / Cosgrove Ave. The journey, including transfers, takes approximately 30h 12m.
No, there is no direct train from Chicago Loop station to Charleston station. However, there are services departing from Chicago Union Station and arriving at Charleston Amtrak Station via Petersburg Amtrak Station. The journey, including transfers, takes approximately 28h 39m.
The distance between Chicago Loop and Charleston is 777 miles. The road distance is 877.8 miles.
The best way to get from Chicago Loop to Charleston without a car is to train which takes 28h 39m and costs $700 - $1,200.
It takes approximately 5h 16m to get from Chicago Loop to Charleston, including transfers.
Chicago Loop to Charleston bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago Loop to Charleston train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago Loop to Charleston is to train which takes 28h 39m and costs $700 - $1,200. Alternatively, you can bus, which costs $190 - $330 and takes 30h 12m, you could also fly, which costs $500 - $900 and takes 5h 31m.
What companies run services between Chicago Loop, IL, USA and Charleston, SC, USA?
You can take a train from Chicago Union Station to Charleston via Petersburg Amtrak Station and Charleston Amtrak Station in around 28h 39m. Alternatively, you can take a bus from Chicago Bus Station to Transit Mall via Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 30h 12m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Charleston International Airport
- Ave. Duration
- 2h 29m
- When
- Every day
- Estimated price
- $75–410
Flights from Chicago O'Hare International Airport to Columbia
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $60–330
Flights from Chicago O'Hare International Airport to Columbia via Washington Dulles
- Ave. Duration
- 4h 34m
- When
- Saturday
- Estimated price
- $75–380
- Website
- southwest.com
Flights from Chicago Midway International Airport to Charleston International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago Midway International Airport to Charleston International Airport via Nashville
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago Midway International Airport to Charleston International Airport via St. Louis
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $130–650
- Website
- delta.com
Flights from Chicago Midway International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $120–650
Flights from Chicago O'Hare International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $80–430
Flights from Chicago O'Hare International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $65–350
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Charleston International Airport
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $75–410
Flights from Chicago O'Hare International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $75–410
Flights from Chicago O'Hare International Airport to Columbia
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $60–330
Flights from Chicago O'Hare International Airport to Columbia via Charlotte
- Ave. Duration
- 4h 17m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–330
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Clark/Lake to Midway
- Ave. Duration
- 27 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $500–800
- Website
- Amtrak
Train from Petersburg Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $200–310
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- 4 times a day
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Atlanta Bus Station to Charleston Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- $80–130
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Chicago Loop to Charleston bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Charleston is 1h ahead of Chicago Loop. It is currently 4:21 AM in Chicago Loop and 5:21 AM in Charleston.
Chicago Loop to Charleston train services, operated by Amtrak, arrive at Petersburg Amtrak Station.
Yes, the driving distance between Chicago Loop to Charleston is 878 miles. It takes approximately 16h to drive from Chicago Loop to Charleston.
Book your Chicago Loop to Charleston train tickets online with Omio.
There are 1813+ hotels available in Charleston.