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How to get fromChicago Midway Airport (MDW) to Buffaloby plane, subway, bus (Greyhound), train (Amtrak), bus, or car

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There are 7 ways to get from Chicago Midway Airport (MDW) to Buffalo by plane, subway, bus (Greyhound), train (Amtrak), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Buffalo Niagara International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    2h 18m
    $163–390

  2. Bus via Cleveland

    cheapest
    1. Take the bus from Chicago to Clevelandbus bus Chicago
    2. Take the bus from Cleveland, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    13h 32m
    $53–146

  3. Subway to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from Midway to Clark/Lakesubway subway
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    4h 49m
    $176–339

  4. Bus (Greyhound)

    1. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    13h 30m
    $86–168

  5. Train (Amtrak)

    1. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    13h 31m
    $168–498

  6. Fly Chicago Midway International Airport to Rochester, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    3h 42m
    $159–757

  7. Drive 532.2 mi

    1. Drive from Chicago Midway Airport (MDW) to Buffalocar car 532.2 mi
    9h 9m
    $98–141

Chicago Midway Airport (MDW) to Buffalo by subway and bus (Greyhound)

Calendar28Weekly Services
Duration13h 30mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Chicago Midway Airport (MDW) to Buffalo.ExpandLaunch map view
  • Distance: 480.6 mi
  • Duration: 2h 18m

What companies run services between Chicago Midway Airport (MDW), USA and Buffalo, NY, USA?

Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF) 4 times a day. Alternatively, you can take a subway from Midway to Buffalo via Washington/Wabash, Michigan & Washington, Harrison & Jefferson, Chicago Bus Station, and Cleveland Bus Station in around 13h 30m.

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