There are 9 ways to get from Chicago Midway Airport (MDW) to Murphysboro by subway, plane, bus, train, taxi, car, train (Amtrak), or rideshare
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago O'Hare International Airport, fly to Williamson County Regional Airport
best- Take the subway from Midway to Clark/Lakesubway
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
4h 7m$130–290Drive 323.9 mi
cheapest- Drive from Chicago Midway Airport (MDW) to Murphysborocar 323.9 mi
5h 39m$60–86Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, bus
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
4h 53m$116–582Bus, train
- Take the bus from Chicago Midway Airport to Illinois Terminalbus Chicago / ...
- Take the train from Champaign-Urbana to Carbondaletrain City of New Orleans / ...
6h 24m$119–203Bus
- Take the bus from Chicago to Marathon Gas Station - Marionbus Chicago / ...
7h 4m$120–248Fly Chicago O'Hare International Airport to Cape Girardeau Municipal Airport, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane ORD - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Murphysborotaxi
5h 12m$210–370Fly Chicago O'Hare International Airport to Barkley Regional Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Drive from Barkley Regional Airport (PAH) to Murphysborocar
5h 16m$62–341Train (Amtrak)
- Take the train from Chicago Union Station to Carbondaletrain Saluki / ...
7h 28m$120–241Airport Transfer
- Take the rideshare from Chicago Midway-MDW to Murphysboro323.9 mi
5h 39m
Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Chicago Midway Airport (MDW) to Murphysboro is to drive which costs $55 - $90 and takes 5h 39m.
The fastest way to get from Chicago Midway Airport (MDW) to Murphysboro is to subway and fly which takes 4h 7m and costs $130 - $290.
No, there is no direct bus from Chicago Midway Airport (MDW) station to Murphysboro station. However, there are services departing from Western Orange Line Station and arriving at Marathon Gas Station - Marion via Chicago. The journey, including transfers, takes approximately 7h 4m.
No, there is no direct train from Chicago Midway Airport (MDW) to Murphysboro. However, there are services departing from Midway and arriving at Carbondale via Chicago Union Station. The journey, including transfers, takes approximately 7h 28m.
The distance between Chicago Midway Airport (MDW) and Murphysboro is 348 miles. The road distance is 325.8 miles.
The best way to get from Chicago Midway Airport (MDW) to Murphysboro without a car is to bus and train which takes 6h 24m and costs $110 - $210.
It takes approximately 4h 7m to get from Chicago Midway Airport (MDW) to Murphysboro, including transfers.
Chicago Midway Airport (MDW) to Murphysboro bus services, operated by Tornado Bus Company, depart from Chicago station.
Chicago Midway Airport (MDW) to Murphysboro train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago Midway Airport (MDW) to Murphysboro is to bus which takes 7h 4m and costs $120 - $250. Alternatively, you can train, which costs $120 - $250 and takes 7h 28m.
What companies run services between Chicago Midway Airport (MDW), USA and Murphysboro, IL, USA?
Tornado Bus Company operates a bus from Chicago to Marathon Gas Station - Marion once daily. Tickets cost $65–180 and the journey takes 5h 5m. Alternatively, Amtrak operates a train from Chicago Union Station to Carbondale 3 times a day. Tickets cost $95–210 and the journey takes 5h 30m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $75–550
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $80–220
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $95–220
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $45–290
- Website
- united.com
Flights from Chicago O'Hare International Airport to Barkley Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $45–310
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Midway to Clark/Lake
- Ave. Duration
- 31 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Champaign-Urbana to Carbondale
- Ave. Duration
- 2h 54m
- Frequency
- 3 times a day
- Estimated price
- $55–120
- Website
- Amtrak
Train from Chicago Union Station to Carbondale
- Ave. Duration
- 5h 30m
- Frequency
- 3 times a day
- Estimated price
- $95–210
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
- Phone
- +1 800-448-0572
- [email protected]
- Website
- Peoria Charter
Bus from Chicago Midway Airport to Illinois Terminal
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Website
- Peoria Charter
- cash
- $60
- online
- $45
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Chicago to Marathon Gas Station - Marion
- Ave. Duration
- 5h 5m
- Frequency
- Once daily
- Estimated price
- $65–180
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $65–180
- Website
- https://www.mozio.com
Rideshare from Chicago Midway-MDW to Murphysboro
- Ave. Duration
- 5h 39m
- Frequency
- On demand
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Chicago Midway Airport (MDW) to Murphysboro bus services, operated by Tornado Bus Company, arrive at Marathon Gas Station - Marion.
Chicago Midway Airport (MDW) to Murphysboro train services, operated by Amtrak, arrive at Carbondale station.
Yes, the driving distance between Chicago Midway Airport (MDW) to Murphysboro is 326 miles. It takes approximately 5h 39m to drive from Chicago Midway Airport (MDW) to Murphysboro.
There are 33+ hotels available in Murphysboro.
Check out Blablacar's carpooling service for rideshare options between Chicago Midway Airport (MDW) and Murphysboro. A great option if you don't have a driver's licence or want to avoid public transport.