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How to get fromChicago Midway Airport (MDW) to Myrtle Beachby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 7 ways to get from Chicago Midway Airport (MDW) to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    2h 6m
    $94–432

  2. Fly from Chicago O'Hare International Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    4h 43m
    $80–364

  3. Bus

    1. Take the bus from Chicago to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    27h 32m
    $170–326

  4. Train, bus via Wilson

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Wilsontrain train
    3. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    31h 59m
    $376–770

  5. Train, bus

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    33h 20m
    $410–877

  6. Train, bus #2

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0645S
    37h 32m
    $412–890

  7. Drive 882.9 mi

    1. Drive from Chicago Midway Airport (MDW) to Myrtle Beachcar car 882.9 mi
    17h 11m
    $162–233

Chicago Midway Airport (MDW) to Myrtle Beach by bus

Calendar14Weekly Buses
Duration27h 32mAverage Duration
Ticket$170Cheapest Price
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Questions & Answers

Map of how to get from Chicago Midway Airport (MDW) to Myrtle Beach.ExpandLaunch map view
  • Distance: 740.8 mi
  • Duration: 2h 6m

What companies run services between Chicago Midway Airport (MDW), USA and Myrtle Beach, SC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) once daily. Alternatively, you can take a bus from Midway Orange Line Station to Myrtle Beach Bus Station via Ashland & 59th Street, 95th Red Line Station, Chicago, and Atlanta Bus Station in around 27h 32m.

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