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How to get fromChicago O'Hare Airport (ORD) to Simpsonvilleby plane, bus (Flixbus, Greyhound), train, bus, taxi, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Chicago O'Hare Airport (ORD) to Simpsonville by plane, bus (Flixbus, Greyhound), train, bus, taxi, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    2h 19m
    $127–549

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    3h 9m
    $71–354

  3. Bus via Auburn Gresham

    1. Take the bus from Chicago to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 35m
    $178–313

  4. Train, bus, taxi

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    2. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Servicios Zapata - Spartanburgbus bus
    4. Take the taxi from Servicios Zapata - Spartanburg to Simpsonvilletaxi taxi
    33h 55m
    $470–953

  5. Drive 698.3 mi

    1. Drive from Chicago O'Hare Airport (ORD) to Simpsonvillecar car 698.3 mi
    13h 21m
    $128–185

  6. Fly to Columbia, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane plane ORD - CAE
    2. Drive from Columbia-Airport-CAE to Simpsonvillecar car
    3h 40m
    $84–387

  7. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    24h 31m
    $164–302

Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) flights

Calendar98Weekly Planes
Duration3h 7mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Chicago O'Hare Airport (ORD) to Simpsonville.ExpandLaunch map view
  • Distance: 590.6 mi
  • Duration: 2h 19m

What companies run services between Chicago O'Hare Airport (ORD), USA and Simpsonville, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a subway from O'Hare to Simpsonville via Jackson-Blue, Jackson-Red, 95th, Chicago, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 35m.

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