There are 5 ways to get from Chicago Union Station to Buffalo Depew Station by subway, plane, train (Amtrak), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly
best- Take the subway from Quincy to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
3h 20m$174–389Bus
cheapest- Take the bus from Chicago to Clevelandbus Chicago
- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
13h 27m$56–143Train (Amtrak)
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
10h 23m$160–350Drive 535.4 mi
- Drive from Chicago Union Station to Buffalo Depew Stationcar 535.4 mi
9h 6m$98–142Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
3h 44m$184–319
Chicago Union Station to Buffalo Depew Station by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago Union Station to Buffalo Depew Station is to bus which costs $55 - $150 and takes 13h 27m.
The fastest way to get from Chicago Union Station to Buffalo Depew Station is to subway and fly which takes 3h 20m and costs $170 - $390.
No, there is no direct bus from Chicago Union Station to Buffalo Depew Station. However, there are services departing from Chicago and arriving at Walden Avenue & 2929 Walden Avenue via Cleveland, OH, Ellicott Street & MTC Static and Walden Avenue & Thruway Transit Center. The journey, including transfers, takes approximately 13h 27m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Buffalo Depew Station station. Services depart twice daily, and operate every day. The journey takes approximately 10h 23m.
The distance between Chicago Union Station and Buffalo Depew Station is 485 miles. The road distance is 538.6 miles.
The best way to get from Chicago Union Station to Buffalo Depew Station without a car is to train which takes 10h 23m and costs $160 - $350.
It takes approximately 3h 20m to get from Chicago Union Station to Buffalo Depew Station, including transfers.
Chicago Union Station to Buffalo Depew Station bus services, operated by Barons Bus, depart from Chicago station.
Chicago Union Station to Buffalo Depew Station train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago Union Station to Buffalo Depew Station is to train which takes 10h 23m and costs $160 - $350. Alternatively, you can bus, which costs $55 - $150 and takes 13h 27m, you could also fly, which costs $180 - $320 and takes 3h 44m.
What companies run services between Chicago Union Station, IL, USA and Buffalo Depew Station, NY, USA?
Amtrak operates a train from Chicago Union Station to Buffalo Depew Station twice daily. Tickets cost $160–350 and the journey takes 10h 23m. Alternatively, you can take a vehicle from Chicago Union Station to Buffalo Depew Station via Chicago, Cleveland, OH, Ellicott Street & MTC Static, Walden Avenue & Thruway Transit Center, and Walden Avenue & 2929 Walden Avenue in around 13h 27m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $85–500
- Website
- delta.com
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $110–650
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $85–500
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $85–500
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Quincy to Midway
- Ave. Duration
- 31 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $160–350
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Chicago to Cleveland
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- Barons Bus
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- Barons Bus
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More Questions & Answers
Chicago Union Station to Buffalo Depew Station bus services, operated by Barons Bus, arrive at Cleveland station.
Buffalo Depew Station is 1h ahead of Chicago Union Station. It is currently 8:34 PM in Chicago Union Station and 9:34 PM in Buffalo Depew Station.
Chicago Union Station to Buffalo Depew Station train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Chicago Union Station to Buffalo Depew Station is 539 miles. It takes approximately 9h 6m to drive from Chicago Union Station to Buffalo Depew Station.
Book your Chicago Union Station to Buffalo Depew Station train tickets online with Omio.
There are 227+ hotels available in Buffalo Depew Station.