What is the cheapest way to get from Chicago Union Station to Des Moines?

The cheapest way to get from Chicago Union Station to Des Moines is to drive which costs $55 - $85 and takes 5h 32m.

What is the fastest way to get from Chicago Union Station to Des Moines?

The fastest way to get from Chicago Union Station to Des Moines is to subway and fly which takes 3h 21m and costs $85 - $470.

Is there a direct bus between Chicago Union Station and Des Moines?

Yes, there is a direct bus departing from Chicago Bus Station station and arriving at Des Moines. Services depart three times a day, and operate every day. The journey takes approximately 6h 30m.

How far is it from Chicago Union Station to Des Moines?

The distance between Chicago Union Station and Des Moines is 324 miles. The road distance is 331.6 miles.

How do I travel from Chicago Union Station to Des Moines without a car?

The best way to get from Chicago Union Station to Des Moines without a car is to bus which takes 6h 39m and costs $60 - $95.

How long does it take to get from Chicago Union Station to Des Moines?

It takes approximately 3h 35m to get from Chicago Union Station to Des Moines, including transfers.

Where do I catch the Chicago Union Station to Des Moines bus from?

Chicago Union Station to Des Moines bus services, operated by Greyhound USA, depart from Chicago Bus Station.

Bus or fly from Chicago Union Station to Des Moines?

The best way to get from Chicago Union Station to Des Moines is to fly which takes 3h 35m and costs $60 - $290. Alternatively, you can bus, which costs $60 - $95 and takes 6h 39m.

Where does the Chicago Union Station to Des Moines bus arrive?

Chicago Union Station to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.

Can I drive from Chicago Union Station to Des Moines?

Yes, the driving distance between Chicago Union Station to Des Moines is 332 miles. It takes approximately 5h 32m to drive from Chicago Union Station to Des Moines.

How do I get a bus ticket from Chicago Union Station to Des Moines?

Book your Chicago Union Station to Des Moines bus tickets online with Omio and FlixBus.

Where can I stay near Des Moines?

There are 239+ hotels available in Des Moines.

Chicago Union Station to Des Moines - 5 ways to travel via train, plane

How to get fromChicago Union Station to Des Moines

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There are 5 ways to get from Chicago Union Station to Des Moines by plane, bus (Greyhound), car, subway, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Chicago O'Hare International Airport
best
1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
3h 35m
$60–288
Drive 329.6 mi
cheapest
1. Drive from Chicago Union Station to Des Moinescar 329.6 mi
5h 32m
$57–82
Bus (Greyhound)
1. Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
6h 39m
$60–95
Subway to Chicago Midway International Airport, fly
1. Take the subway from Quincy to Midwaysubway
2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
3h 21m
$86–468
Train, bus
1. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain Southwest Chief / ...
2. Take the bus from Galesburg to Des Moinesbus Greyhound US0157S
8h 31m
$124–197

Chicago Union Station to Des Moines by foot and bus (Greyhound)

18Weekly Services

6h 39mAverage Duration

$60Cheapest Price

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Comparing Your Travel Options

Map of how to get from Chicago Union Station to Des Moines.

Launch map view

Distance: 322.5 mi
Duration: 3h 35m

What companies run services between Chicago Union Station, IL, USA and Des Moines, IA, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 3 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $60–95 and the journey takes 6h 30m.

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