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How to get fromChicago Union Station to Gainesvilleby plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Chicago Union Station to Gainesville by plane, bus, bus (Greyhound), train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Hartsfield-Jackson Atlanta International Airport, bus

    best
    1. Fly from Chicago Midway International Airport (MDW) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MDW - ATL
    2. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus
    6h 30m
    $130–330

  2. Drive 663.5 mi

    cheapest
    1. Drive from Chicago Union Station to Gainesvillecar car 663.5 mi
    13h 17m
    $122–175

  3. Bus (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus Greyhound US0670
    18h 33m
    $126–232

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Charlottesvilletrain train Cardinal
    2. Take the train from Charlottesville to Gainesville Stationtrain train Crescent
    32h 13m
    $392–836

  5. Fly Chicago O'Hare International Airport to Hartsfield-Jackson Atlanta International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane ORD - ATL
    2. Take the bus from Atlanta to BB Wireless - Gainesvillebus bus
    6h 54m
    $240–510

  6. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    2. Take the bus from Taqueria Guadalajara - Greenville to BB Wireless - Gainesvillebus bus
    7h 49m
    $192–762

  7. Fly Chicago O'Hare International Airport to Mcghee Tyson Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Gainesvillecar car
    7h 20m
    $130–650

  8. Bus via Chicago Bus Station

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus Greyhound US0670
    18h 42m
    $126–233

Chicago Union Station to Gainesville by train (Amtrak)

Calendar3Weekly Trains
Duration32h 13mAverage Duration
Ticket$392Cheapest Price
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Questions & Answers

Map of how to get from Chicago Union Station to Gainesville.ExpandLaunch map view
  • Distance: 668.2 mi
  • Duration: 6h 30m

What companies run services between Chicago Union Station, IL, USA and Gainesville, GA, USA?

You can take a bus from Chicago Train Station to Gainesville via Atlanta Bus Station and Gainesville in around 18h 33m. Alternatively, you can take a train from Chicago Union Station to Gainesville Station via Charlottesville in around 32h 13m.

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