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How to get fromChicago Union Station to Myrtle Beachby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 8 ways to get from Chicago Union Station to Myrtle Beach by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Myrtle Beach

    best
    1. Fly from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR)plane plane MDW - MYR
    3h 56m
    $98–449

  2. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus FlixBus 2512 / ...
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641
    24h 14m
    $175–336

  3. Train, bus via Wilson

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Wilsontrain train
    3. Take the bus from Wilson to Wilmington Amtrak Stationbus bus
    4. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    30h 15m
    $387–754

  4. Drive 883 mi

    1. Drive from Chicago Union Station to Myrtle Beachcar car 883 mi
    17h 6m
    $162–233

  5. Fly Chicago O'Hare International Airport to Myrtle Beach

    1. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    4h 25m
    $304–819

  6. Fly Chicago O'Hare International Airport to Wilmington International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Wilmington International Airport (ILM)plane plane ORD - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    7h 2m
    $108–446

  7. Train, bus

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    31h 41m
    $420–861

  8. Train, bus #2

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Raleigh Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0645S
    35h 44m
    $420–839

Chicago Union Station to Myrtle Beach by foot and bus

Calendar14Weekly Services
Duration24h 14mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

Map of how to get from Chicago Union Station to Myrtle Beach.ExpandLaunch map view
  • Distance: 753.6 mi
  • Duration: 3h 56m

What companies run services between Chicago Union Station, IL, USA and Myrtle Beach, SC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Myrtle Beach (MYR) once daily. Alternatively, you can take a vehicle from Chicago Union Station to Myrtle Beach Bus Station via Chicago Bus Station and Atlanta Bus Station in around 24h 14m.

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