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How to get fromChicago Union Station to Saint Charlesby plane, train (Amtrak), bus, taxi, car, or subway

Find Transport to Saint Charles

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There are 5 ways to get from Chicago Union Station to Saint Charles by plane, train (Amtrak), bus, taxi, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    3h 56m
    $128–560
  2. Drive 359.7 mi

    cheapest
    1. Drive from Chicago Union Station to Saint Charlescar car 359.7 mi
    6h 6m
    $66–95
  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Osceola Amtraktrain train California Zephyr
    6h 45m
    $155–291
  4. Bus, taxi

    1. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    2. Take the taxi from Des Moines to Saint Charlestaxi taxi
    7h 20m
    $125–184
  5. Subway to Chicago Midway International Airport, fly

    1. Take the subway from Quincy to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    3h 40m
    $142–670

Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights

Calendar63Weekly Planes
Duration1h 30mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

What companies run services between Chicago Union Station, IL, USA and Saint Charles, IA, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 3 hours. Alternatively, Amtrak operates a train from Chicago Union Station to Osceola Amtrak once daily. Tickets cost $110–240 and the journey takes 6h 23m.

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