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How to get fromChicago to Annaby train (Amtrak), bus, car, plane, or taxi

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There are 7 ways to get from Chicago to Anna by train (Amtrak), bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to Carbondaletrain train Saluki / ...
    5h 55m
    $146–256

  2. Drive 345.5 mi

    cheapest
    1. Drive from Chicago to Annacar car 345.5 mi
    5h 43m
    $64–92

  3. Bus

    1. Take the bus from Chicago to Anna - Shellbus bus Chicago
    7h 11m
    $88–200

  4. Fly to Williamson County Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Annataxi taxi
    3h 45m
    $158–315

  5. Bus via Carbondale Intermodal Station

    1. Take the bus from Chicago Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    9h 30m
    $143–189

  6. Fly to Cape Girardeau Municipal Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Annataxi taxi
    4h 9m
    $172–310

  7. Fly to Barkley Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Annataxi taxi
    4h 21m
    $172–455

Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights

Calendar19Weekly Planes
Duration1h 31mAverage Duration
Ticket$49Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Anna.ExpandLaunch map view
  • Distance: 328.8 mi
  • Duration: 5h 55m

What companies run services between Chicago, IL, USA and Anna, IL, USA?

Amtrak operates a train from Chicago Union Station to Carbondale 3 times a day. Tickets cost $100–210 and the journey takes 5h 30m. Alternatively, Tornado Bus Company operates a bus from Chicago to Anna - Shell once daily. Tickets cost $70–180 and the journey takes 5h 25m.

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