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How to get fromChicago to Cape Girardeauby plane, train, taxi, bus, car, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Chicago to Cape Girardeau by plane, train, taxi, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Cape Girardeau Municipal Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3h 38m
    $120–243

  2. Drive 371.6 mi

    cheapest
    1. Drive from Chicago to Cape Girardeaucar car 371.6 mi
    6h 17m
    $68–98

  3. Train, taxi

    1. Take the train from Chicago Union Station to Carbondaletrain train Saluki / ...
    2. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    6h 30m
    $201–331

  4. Bus, taxi

    1. Take the bus from Chicago to Anna - Shellbus bus Chicago
    2. Take the taxi from Anna - Shell to Cape Girardeautaxi taxi
    7h 44m
    $146–278

  5. Fly Chicago O'Hare International Airport to Williamson County Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    4h 19m
    $218–385

  6. Fly Chicago O'Hare International Airport to Barkley Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    4h 45m
    $192–475

  7. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 52m
    $318–767

  8. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    6h 36m
    $128–617

  9. Train, bus

    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    7h 55m
    $133–242

  10. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    9h 4m
    $94–143

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Cape Girardeau.ExpandLaunch map view
  • Distance: 365.4 mi
  • Duration: 3h 38m

What companies run services between Chicago, IL, USA and Cape Girardeau, MO, USA?

Corporate Flight Management Inc flies from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) once daily. Alternatively, you can take a bus from Chicago Bus Station to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 9h 4m.

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