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How to get fromChicago to Cayenneby plane, train, or shuttle

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There are 4 ways to get from Chicago to Cayenne by plane, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Cayenne (CAY)plane plane ORD - CAY
    15h 30m
    $502–2,005

  2. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Cayenne (CAY)plane plane MDW - CAY
    31h 49m
    $702–2,805

  3. Train to South Bend, fly

    1. Take the train from Van Buren St. to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Cayenne (CAY)plane plane SBN - CAY
    40h 49m
    $565–2,216

  4. Train, shuttle to Indianapolis, fly

    1. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    2. Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airportshuttle bus
    3. Fly from Indianapolis (IND) to Cayenne (CAY)plane plane IND - CAY
    30h 35m
    $693–2,804

Chicago O'Hare International Airport (ORD) to Cayenne (CAY) flights

Calendar3Weekly Planes
Duration16h 5mAverage Duration
Ticket$506Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Cayenne.ExpandLaunch map view
  • Distance: 5,470.6 km
  • Duration: 15h 30m

What companies run services between Chicago, IL, USA and Cayenne, French Guiana?

American Airlines, Air France, and Air Canada fly from Chicago O'Hare International Airport (ORD) to Cayenne (CAY) 3 times a week.

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Want to know more about travelling around French Guiana

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