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How to get fromChicago to Charlestonby subway, plane, train (Amtrak), bus (Greyhound, Flixbus), or car

Find Transport to Charleston

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There are 6 ways to get from Chicago to Charleston by subway, plane, train (Amtrak), bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly to Charleston International Airport

    best
    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    5h 12m
    $114–607

  2. Fly Chicago O'Hare International Airport to Columbia, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane plane ORD - CAE
    2. Drive from Columbia-Airport-CAE to Charlestoncar car
    5h 40m
    $82–375

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train Floridian
    2. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 39m
    $379–931

  4. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    30h 12m
    $188–305

  5. Drive  872.2 mi

    1. Drive from Chicago to Charlestoncar car 872.2 mi
    15h 59m
    $160–230

  6. Fly Chicago O'Hare International Airport to Charleston International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    5h 35m
    $554–807

Chicago to Charleston by bus

Calendar7Weekly Buses
Duration30h 12mAverage Duration
Ticket$188Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Charleston.ExpandLaunch map view
  • Distance: 771.4 mi
  • Duration: 5h 12m

What companies run services between Chicago, IL, USA and Charleston, SC, USA?

You can take a train from Chicago Union Station to Charleston via Petersburg Amtrak Station and Charleston Amtrak Station in around 28h 39m. Alternatively, you can take a bus from Chicago Bus Station to Transit Mall via Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 30h 12m.

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Need to know: Greyhound

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