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How to get fromChicago to Charlotteby plane, bus, train (Amtrak), car, train, or bus (Amtrak, Greyhound)

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There are 8 ways to get from Chicago to Charlotte by plane, bus, train (Amtrak), car, train, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago Midway International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    4h 4m
    $136–808

  2. Bus

    cheapest
    1. Take the bus from Chicago to Columbusbus bus Bsb 22 / ...
    2. Take the bus from Columbus to Charlottebus bus Bsb 32
    18h 50m
    $77–175

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train Piedmont / ...
    28h 24m
    $684–1,051

  4. Drive  728.5 mi

    1. Drive from Chicago to Charlottecar car 728.5 mi
    13h 28m
    $133–192

  5. Fly from Chicago O'Hare International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    4h 27m
    $90–508

  6. Train to South Bend, fly

    1. Take the train from Van Buren St. to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Charlotte Douglas International Airport (CLT)plane plane SBN - CLT
    5h 42m
    $118–619

  7. Train to General Mitchell International Airport, fly

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)plane plane MKE - CLT
    5h 45m
    $202–939

  8. Bus via Toledo

    1. Take the bus from Chicago Union Station to Toledobus bus Amtrak Thruway Connecting Service
    2. Take the bus from Toledo Bus Stop to Charlotte Bus Stationbus bus Greyhound US0140
    19h 33m

Chicago to Charlotte by bus

Calendar7Weekly Buses
Duration18h 50mAverage Duration
Ticket$77Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chicago to Charlotte.ExpandLaunch map view
  • Distance: 602.1 mi
  • Duration: 4h 4m

What companies run services between Chicago, IL, USA and Charlotte, NC, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT) 5 times a day. Alternatively, you can take a bus from Chicago to Charlotte via Columbus in around 18h 50m.

Airlines
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