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How to get fromChicago to Chillicotheby train, car, plane, or shuttle

Find Transport to Chillicothe

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There are 5 ways to get from Chicago to Chillicothe by train, car, plane, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, drive (Amtrak)

    best
    1. Take the train from Chicago Union Station to La Plata Stationtrain train Southwest Chief
    2. Drive from La Plata Station to Chillicothecar car
    6h 18m
    $109–217

  2. Drive 419.7 mi

    cheapest
    1. Drive from Chicago to Chillicothecar car 419.7 mi
    7h 9m
    $77–111

  3. Fly Chicago O'Hare International Airport to Columbia Regional Airport, shuttle, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    2. Take a shuttle bus from Columbia to Maconshuttle bus
    3. Drive from Macon to Chillicothecar car
    6h 33m
    $112–391

  4. Fly Chicago Midway International Airport to Kansas City, shuttle

    1. Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane plane MDW - MCI
    2. Take a shuttle bus from Kansas City to Chillicotheshuttle bus
    7h 43m
    $106–661

  5. Fly Chicago O'Hare International Airport to Kansas City, shuttle

    1. Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane plane ORD - MCI
    2. Take a shuttle bus from Kansas City to Chillicotheshuttle bus
    8h 5m
    $356–761

Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU) flights

Calendar42Weekly Planes
Duration1h 32mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Chillicothe.ExpandLaunch map view
  • Distance: 377 mi
  • Duration: 6h 18m

What companies run services between Chicago, IL, USA and Chillicothe, MO, USA?

There is no direct connection from Chicago to Chillicothe. However, you can take the train to La Plata Station then drive to Chillicothe. Alternatively, you can drive from Chicago to Chillicothe in around 7h 9m.

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