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How to get fromChicago to Clarksdaleby plane, car, bus, taxi, or train (Amtrak)

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There are 7 ways to get from Chicago to Clarksdale by plane, car, bus, taxi, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Bill And Hillary Clinton National Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Bill And Hillary Clinton National Airport (LIT)plane plane ORD - LIT
    2. Drive from Bill And Hillary Clinton National Airport (LIT) to Clarksdalecar car
    6h 32m
    $168–845

  2. Drive 605.2 mi

    cheapest
    1. Drive from Chicago to Clarksdalecar car 605.2 mi
    10h
    $111–160

  3. Bus, taxi

    1. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus bus
    3. Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi taxi
    12h 25m
    $212–323

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Marks Stationtrain train City of New Orleans
    12h 44m
    $246–452

  5. Fly Chicago Midway International Airport to Bill And Hillary Clinton National Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Bill And Hillary Clinton National Airport (LIT)plane plane MDW - LIT
    2. Drive from Bill And Hillary Clinton National Airport (LIT) to Clarksdalecar car
    8h 30m
    $238–1,145

  6. Fly Chicago O'Hare International Airport to Memphis, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM)plane plane ORD - MEM
    2. Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus bus
    3. Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi taxi
    7h 59m
    $228–773

  7. Fly Chicago Midway International Airport to Memphis, bus, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Memphis (MEM)plane plane MDW - MEM
    2. Take the bus from Memphis Bus Station to Batesville(Terza One Stop Shop)bus bus
    3. Take the taxi from Batesville(Terza One Stop Shop) to Clarksdaletaxi taxi
    7h 33m
    $252–923

Chicago O'Hare International Airport (ORD) to Bill And Hillary Clinton National Airport (LIT) flights

Calendar68Weekly Planes
Duration2h 32mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Clarksdale.ExpandLaunch map view
  • Distance: 711.7 mi
  • Duration: 6h 32m

What companies run services between Chicago, IL, USA and Clarksdale, MS, USA?

Amtrak operates a train from Chicago Union Station to Marks Station once daily. Tickets cost $190–390 and the journey takes 12h 20m.

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