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How to get fromChicago to Du Quoinby train (Amtrak), car, plane, or taxi

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There are 5 ways to get from Chicago to Du Quoin by train (Amtrak), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to Du Quoin Stationtrain train Saluki / ...
    5h 2m
    $95–190

  2. Drive 308 mi

    cheapest
    1. Drive from Chicago to Du Quoincar car 308 mi
    5h 32m
    $57–82

  3. Fly to Williamson County Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Du Quointaxi taxi
    3h 55m
    $158–310

  4. Fly to Barkley Regional Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to Du Quoincar car
    5h 4m
    $62–338

  5. Fly to Cape Girardeau Municipal Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Drive from Cape Girardeau Municipal Airport (CGI) to Du Quoincar car
    5h 4m
    $110–234

Chicago to Du Quoin by train (Amtrak)

Calendar14Weekly Trains
Duration5h 2mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Du Quoin.ExpandLaunch map view
  • Distance: 288.8 mi
  • Duration: 5h 2m

What companies run services between Chicago, IL, USA and Du Quoin, IL, USA?

Amtrak operates a train from Chicago Union Station to Du Quoin Station twice daily. Tickets cost $95–190 and the journey takes 5h 2m.

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