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How to get fromChicago to Durham Amtrak Stationby subway, plane, bus, bus (Amtrak, Greyhound), train (Amtrak), car, or train

Find Transport to Durham Amtrak Station

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There are 6 ways to get from Chicago to Durham Amtrak Station by subway, plane, bus, bus (Amtrak, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Durham Stationbus bus
    4h 55m
    $158–311

  2. Drive 752.2 mi

    cheapest
    1. Drive from Chicago to Durham Amtrak Stationcar car 752.2 mi
    14h 5m
    $138–199

  3. Bus

    1. Take the bus from Chicago Union Station to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    20h 48m
    $182–313

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train Floridian
    26h 13m
    $358–717

  5. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport, bus, line 700 bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Durham Stationbus bus
    5h 18m
    $178–761

  6. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 3m
    $148–680

Chicago to Durham Amtrak Station by bus

Calendar2Weekly Buses
Duration20h 48mAverage Duration
Ticket$182Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Durham Amtrak Station.ExpandLaunch map view
  • Distance: 659.1 mi
  • Duration: 4h 55m

What companies run services between Chicago, IL, USA and Durham Amtrak Station, NC, USA?

You can take a bus from Chicago Union Station to Durham via Toledo Bus Stop and Winston Salem(Trans Center) in around 20h 48m. Alternatively, Amtrak operates a train from Chicago Union Station to Cary once daily. Tickets cost $350–750 and the journey takes 24h 26m.

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Train operators
Bus operators

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