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How to get fromChicago to Gainesvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 10 ways to get from Chicago to Gainesville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Gainesville Regional Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV)plane plane MDW - GNV
    6h 57m
    $144–497

  2. Fly Chicago O'Hare International Airport to Gainesville Regional Airport

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV)plane plane ORD - GNV
    7h 13m
    $84–407

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus FlixBus N2401 / ...
    22h 15m
    $145–266

  4. Train, bus

    1. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Gainesvillebus bus FlixBus 2431
    38h 15m
    $427–934

  5. Drive 996.5 mi

    1. Drive from Chicago to Gainesvillecar car 996.5 mi
    18h
    $182–263

  6. Fly Chicago Midway International Airport to Jacksonville, bus

    1. Fly from Chicago Midway International Airport (MDW) to Jacksonville (JAX)plane plane MDW - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    7h 57m
    $172–574

  7. Fly Chicago O'Hare International Airport to Jacksonville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Jacksonville (JAX)plane plane ORD - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    8h 28m
    $192–524

  8. Fly Chicago Midway International Airport to Orlando, bus

    1. Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane plane MDW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 46m
    $222–542

  9. Fly Chicago Midway International Airport to Tampa, bus

    1. Fly from Chicago Midway International Airport (MDW) to Tampa (TPA)plane plane MDW - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    8h 22m
    $122–436

  10. Bus via North Walmart Supercenter (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus Greyhound US0630
    25h 3m
    $149–283

Chicago to Gainesville by bus

Calendar34Weekly Buses
Duration22h 15mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Gainesville.ExpandLaunch map view
  • Distance: 908.4 mi
  • Duration: 6h 57m

What companies run services between Chicago, IL, USA and Gainesville, FL, USA?

Delta, Southwest Airlines, and two other airlines fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV) 4 times a day. Alternatively, you can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 22h 15m.

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