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How to get fromChicago to Greenville Amtrak Stationby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or taxi

Find Transport to Greenville Amtrak Station

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There are 7 ways to get from Chicago to Greenville Amtrak Station by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    4h 6m
    $138–605

  2. Drive 666.9 mi

    cheapest
    1. Drive from Chicago to Greenville Amtrak Stationcar car 666.9 mi
    12h 43m
    $122–176

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 21m
    $173–378

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to Charlottesvilletrain train Cardinal
    2. Take the train from Charlottesville to Greenville Amtrak Stationtrain train Crescent
    30h 12m
    $366–777

  5. Fly Chicago O'Hare International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenville Amtrak Stationtaxi taxi
    4h 39m
    $192–515

  6. Fly Chicago Midway International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Asheville Regional Airport (AVL)plane plane MDW - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenville Amtrak Stationtaxi taxi
    6h 21m
    $228–665

  7. Train via Cary (Amtrak)

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the train from Charlotte Amtrak Station to Greenville Amtrak Stationtrain train
    31h 53m
    $424–893

Chicago to Greenville Amtrak Station by train (Amtrak)

Calendar3Weekly Trains
Duration30h 12mAverage Duration
Ticket$366Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Greenville Amtrak Station.ExpandLaunch map view
  • Distance: 609.5 mi
  • Duration: 4h 6m

What companies run services between Chicago, IL, USA and Greenville Amtrak Station, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Chicago Bus Station to Greenville Amtrak Station via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 21m.

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