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How to get fromChicago to Greenvilleby train, taxi, bus, car, or plane

Find Transport to Greenville

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There are 7 ways to get from Chicago to Greenville by train, taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi (Amtrak)

    best
    1. Take the train from Chicago Union Station to Centralia Amtraktrain train Saluki / ...
    2. Take the taxi from Centralia Amtrak to Greenvilletaxi taxi
    5h 28m
    $166–276

  2. Drive 261.7 mi

    cheapest
    1. Drive from Chicago to Greenvillecar car 261.7 mi
    4h 22m
    $48–69

  3. Bus, taxi

    1. Take the bus from Chicago to Lupita's Grocery - Effinghambus bus Chicago
    2. Take the taxi from Lupita's Grocery - Effingham to Greenvilletaxi taxi
    5h 57m
    $168–302

  4. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, train, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    3. Take the taxi from SHILOH-SCOTT station to Greenvilletaxi taxi
    5h 23m
    $366–828

  5. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, train, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to SHILOH-SCOTT stationtrain train
    3. Take the taxi from SHILOH-SCOTT station to Greenvilletaxi taxi
    5h 7m
    $170–678

  6. Fly Chicago O'Hare International Airport to Abraham Lincoln Capital Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Abraham Lincoln Capital Airport (SPI)plane plane ORD - SPI
    2. Drive from Abraham Lincoln Capital Airport (SPI) to Greenvillecar car
    4h 36m
    $50–295

  7. Fly Chicago O'Hare International Airport to Decatur Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Decatur Airport (DEC)plane plane ORD - DEC
    2. Drive from Decatur Airport (DEC) to Greenvillecar car
    4h 54m
    $54–299

Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) flights

Calendar109Weekly Planes
Duration1h 28mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Greenville.ExpandLaunch map view
  • Distance: 291.3 mi
  • Duration: 5h 28m

What companies run services between Chicago, IL, USA and Greenville, IL, USA?

There is no direct connection from Chicago to Greenville. However, you can take the train to Centralia Amtrak then take the taxi to Greenville. Alternatively, you can take the line 62 bus to 35th/Archer Orange Line Station, take the line 35 bus to California & 35th Street, walk to Chicago, take the bus to Lupita's Grocery - Effingham, then take the taxi to Greenville.

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