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How to get fromChicago to Greenvilleby plane, car, train, bus, or taxi

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There are 8 ways to get from Chicago to Greenville by plane, car, train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Erie International Airport, drive

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Erie International Airport (ERI)plane plane ORD - ERI
    2. Drive from Erie-Airport-ERI to Greenvillecar car
    4h 41m
    $62–340

  2. Train, bus, taxi via Cleveland

    1. Take the train from Chicago Union Station to Cleveland Amtraktrain train
    2. Take the bus from Cleveland, OH to Youngstownbus bus
    3. Take the taxi from Youngstown to Greenvilletaxi taxi
    9h 36m
    $281–416

  3. Bus, taxi

    1. Take the bus from Chicago Bus Station to Youngstown Bus Stopbus bus Greyhound US0164
    2. Take the taxi from Youngstown Bus Stop to Greenvilletaxi taxi
    9h 50m
    $143–218

  4. Drive 410.4 mi

    1. Drive from Chicago to Greenvillecar car 410.4 mi
    7h 10m
    $75–109

  5. Fly Chicago Midway International Airport to Cleveland-Hopkins International Airport, bus, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Cleveland-Hopkins International Airport (CLE)plane plane MDW - CLE
    2. Take the bus from Cleveland Bus Station to Youngstown Bus Stopbus bus
    3. Take the taxi from Youngstown Bus Stop to Greenvilletaxi taxi
    6h 14m
    $176–680

  6. Fly Chicago O'Hare International Airport to Cleveland-Hopkins International Airport, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Cleveland-Hopkins International Airport (CLE)plane plane ORD - CLE
    2. Take the bus from Cleveland Bus Station to Youngstown Bus Stopbus bus
    3. Take the taxi from Youngstown Bus Stop to Greenvilletaxi taxi
    6h 42m
    $466–930

  7. Fly Chicago O'Hare International Airport to Akron, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Akron (CAK)plane plane ORD - CAK
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Youngstown Bus Stopbus bus
    3. Take the taxi from Youngstown Bus Stop to Greenvilletaxi taxi
    7h 38m
    $124–348

  8. Train, bus, taxi

    1. Take the train from Van Buren St. to Gary Metro Centertrain train Ssl
    2. Take the bus from Gary Bus Station to Youngstown Bus Stopbus bus
    3. Take the taxi from Youngstown Bus Stop to Greenvilletaxi taxi
    11h 1m
    $153–218

Chicago O'Hare International Airport (ORD) to Erie International Airport (ERI) flights

Calendar14Weekly Planes
Duration1h 41mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Greenville.ExpandLaunch map view
  • Distance: 471.1 mi
  • Duration: 4h 41m

What companies run services between Chicago, IL, USA and Greenville, Mercer County, PA, USA?

There is no direct connection from Chicago to Greenville. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Erie International Airport (ERI), then drive to Greenville. Alternatively, you can take the train to Cleveland Amtrak, walk to Prospect Av & W 3Rd St, take the line 9 bus to Payne Av & E 30Th St, walk to Cleveland, OH, take the bus to Youngstown, then take the taxi to Greenville.

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