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How to get fromChicago to Greenvilleby plane, bus, bus (Greyhound, Flixbus), train, or car

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There are 10 ways to get from Chicago to Greenville by plane, bus, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Norfolk International Airport, bus

    best
    1. Fly from Chicago Midway International Airport (MDW) to Norfolk International Airport (ORF)plane plane MDW - ORF
    2. Take the bus from Norfolk to Greenville GK Butterfield Trans Ctrbus bus
    7h 47m
    $132–568

  2. Fly Chicago Midway International Airport to Greenville

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Greenville (PGV)plane plane MDW - PGV
    8h 2m
    $100–494

  3. Bus

    1. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    25h
    $155–302

  4. Train, bus

    1. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    2. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus Greyhound US0652s / ...
    27h 14m
    $344–720

  5. Drive 852.9 mi

    1. Drive from Chicago to Greenvillecar car 852.9 mi
    15h 51m
    $156–225

  6. Fly Chicago O'Hare International Airport to Wilmington International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Wilmington International Airport (ILM)plane plane ORD - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Greenville GK Butterfield Trans Ctrbus bus
    8h 49m
    $112–473

  7. Fly Chicago O'Hare International Airport to Norfolk International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Norfolk International Airport (ORF)plane plane ORD - ORF
    2. Take the bus from Norfolk to Greenville GK Butterfield Trans Ctrbus bus
    8h 17m
    $116–478

  8. Fly Chicago Midway International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    2. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    8h 6m
    $170–333

  9. Fly Chicago O'Hare International Airport to Raleigh-Durham International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    2. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    8h 30m
    $190–783

  10. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, train, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the train from Greensboro to Wilsontrain train
    3. Take the bus from Wilson Bus Stop to Greenville GK Butterfield Trans Ctrbus bus
    9h 37m
    $176–747

Chicago to Greenville by bus

Calendar14Weekly Buses
Duration25hAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Greenville.ExpandLaunch map view
  • Distance: 858 mi
  • Duration: 7h 47m

What companies run services between Chicago, IL, USA and Greenville, Pitt County, NC, USA?

You can take a bus from Chicago Bus Station to Greenville GK Butterfield Trans Ctr via Washington Union Station and Raleigh Bus Station in around 25h. Alternatively, Southwest Airlines, American Airlines, and Allegiant Air fly from Chicago Midway International Airport (MDW) to Greenville (PGV) once daily.

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