There are 5 ways to get from Chicago to Guayaquil by plane, train, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE)plane ORD - GYE
11h 14m$162–655Fly Chicago O'Hare International Airport to Eloy Alfaro International Airport, bus
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Eloy Alfaro International Airport (MEC)plane ORD - MEC
- Take the bus from Manta to Terminal Terrestre de Guayaquilbus
15h 41m$160–620Train to General Mitchell International Airport, fly to José Joaquín De Olmedo International Airport
- Take the train from Chicago Union Station to Milwaukeetrain
- Fly from General Mitchell International Airport (MKE) to José Joaquín De Olmedo International Airport (GYE)plane MKE - GYE
13h 39m$319–1,186Fly Chicago Midway International Airport to José Joaquín De Olmedo International Airport
- Fly from Chicago Midway International Airport (MDW) to José Joaquín De Olmedo International Airport (GYE)plane MDW - GYE
11h 25m$252–1,005Train, shuttle to Indianapolis, fly to José Joaquín De Olmedo International Airport
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
- Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airport
- Fly from Indianapolis (IND) to José Joaquín De Olmedo International Airport (GYE)plane IND - GYE
15h 21m$310–1,037
Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE) flights
Comparing Your Travel Options
The cheapest way to get from Chicago to Guayaquil is to fly and bus which costs $160 - $650 and takes 15h 41m.
The fastest way to get from Chicago to Guayaquil is to fly which takes 11h 14m and costs $160 - $700.
The distance between Chicago and Guayaquil is 5001 km.
It takes approximately 11h 14m to get from Chicago to Guayaquil, including transfers.
There are 411+ hotels available in Guayaquil.
What companies run services between Chicago, IL, USA and Guayaquil, Ecuador?
JetBlue Airways, Copa Airlines, and five other airlines fly from Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE) every 4 hours.
- Website
- copaair.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Panama City
- Ave. Duration
- 8h 49m
- When
- Every day
- Estimated price
- $160–650
Flights from General Mitchell International Airport to José Joaquín De Olmedo International Airport via Orlando, Panama City
- Ave. Duration
- 10h 54m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $270–1,100
Flights from Chicago Midway International Airport to José Joaquín De Olmedo International Airport via Tampa, Panama City
- Ave. Duration
- 14h 8m
- When
- Monday, Thursday, and Friday
- Estimated price
- $250–1,000
Flights from Chicago O'Hare International Airport to Eloy Alfaro International Airport via Panama City
- Ave. Duration
- 8h 47m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- $150–600
Flights from Chicago O'Hare International Airport to Eloy Alfaro International Airport via Orlando, Panama City
- Ave. Duration
- 10h 22m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- $150–600
- Website
- aa.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 12h 2m
- When
- Every day
- Estimated price
- $160–650
Flights from General Mitchell International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 12h 41m
- When
- Saturday
- Estimated price
- $270–1,100
Flights from Chicago Midway International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 8h 51m
- When
- Tuesday and Wednesday
- Estimated price
- $250–1,000
Flights from Indianapolis to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 9h 46m
- When
- Every day
- Estimated price
- $230–900
- Website
- jetblue.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Fort Lauderdale
- Ave. Duration
- 8h 29m
- When
- Every day
- Estimated price
- $160–650
Flights from Indianapolis to José Joaquín De Olmedo International Airport via Fort Lauderdale
- Ave. Duration
- 10h 9m
- When
- Every day
- Estimated price
- $230–900
- Website
- latam.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 13h 2m
- When
- Every day
- Estimated price
- $280–850
Flights from General Mitchell International Airport to José Joaquín De Olmedo International Airport via Atlanta, Quito
- Ave. Duration
- 19h 42m
- When
- Thursday
- Estimated price
- $270–1,100
Flights from Indianapolis to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 14h 3m
- When
- Every day
- Estimated price
- $420–1,300
- Website
- delta.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 13h 2m
- When
- Every day
- Estimated price
- $280–850
Flights from Indianapolis to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 14h 3m
- When
- Every day
- Estimated price
- $420–1,300
- Website
- avianca.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 9h 30m
- When
- Every day
- Estimated price
- $310–1,000
- Website
- arajet.com
Flights from General Mitchell International Airport to José Joaquín De Olmedo International Airport via Punta Cana
- Ave. Duration
- 16h 12m
- When
- Friday
- Estimated price
- $300–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $65–110
- Website
- Amtrak
- Phone
- +1 800-589-6004
- [email protected]
- Website
- Go Express Travel
Shuttle from Holiday Inn City Centre to Indianapolis Airport
- Ave. Duration
- 1h 25m
- Frequency
- On demand
- Estimated price
- $33
- Schedules at
- Go Express Travel
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from Holiday Inn City Centre to Indianapolis Airport
- Ave. Duration
- 1h 49m
- Frequency
- Every 3 hours
- Estimated price
- $14–28
- Schedules at
- lafayettelimo.com
- Child
- $14–23
- Adult
- $24–28
- [email protected]
- Website
- Cooperativa Reina del Camino
Bus from Manta to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Cooperativa Reina del Camino
Want to know more about travelling around Ecuador
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