There are 4 ways to get from Chicago to Guayaquil by plane, train, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE)plane ORD - GYE
11h 21m$202–755Fly Chicago Midway International Airport to José Joaquín De Olmedo International Airport
- Fly from Chicago Midway International Airport (MDW) to José Joaquín De Olmedo International Airport (GYE)plane MDW - GYE
11h 39m$262–955Train, shuttle to Indianapolis, fly to José Joaquín De Olmedo International Airport
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
- Take a shuttle bus from Holiday Inn City Centre to Indianapolis Airport
- Fly from Indianapolis (IND) to José Joaquín De Olmedo International Airport (GYE)plane IND - GYE
15h 30m$294–1,064Fly Chicago O'Hare International Airport to Eloy Alfaro International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Eloy Alfaro International Airport (MEC)plane ORD - MEC
- Take the bus from Manta to Terminal Terrestre de Guayaquilbus
16h 19m$210–770
Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE) flights
Questions & Answers
The cheapest way to get from Chicago to Guayaquil is to fly which costs $200 - $800 and takes 11h 21m.
The fastest way to get from Chicago to Guayaquil is to fly which takes 11h 21m and costs $200 - $800.
The distance between Chicago and Guayaquil is 5001 km.
It takes approximately 11h 21m to get from Chicago to Guayaquil, including transfers.
There are 451+ hotels available in Guayaquil.
What companies run services between Chicago, IL, USA and Guayaquil, Ecuador?
Copa Airlines, Avianca - Aerovías del Continente Americano S.A., and three other airlines fly from Chicago O'Hare International Airport (ORD) to José Joaquín De Olmedo International Airport (GYE) every 4 hours.
- Website
- copaair.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Panama City
- Ave. Duration
- 9h 5m
- When
- Every day
- Estimated price
- $200–750
Flights from Chicago Midway International Airport to José Joaquín De Olmedo International Airport via Tampa, Panama City
- Ave. Duration
- 12h 32m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $260–950
Flights from Chicago O'Hare International Airport to Eloy Alfaro International Airport via Panama City
- Ave. Duration
- 9h 24m
- When
- Every day
- Estimated price
- $200–750
- Website
- jetblue.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Fort Lauderdale
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $200–750
Flights from Chicago Midway International Airport to José Joaquín De Olmedo International Airport via Fort Lauderdale
- Ave. Duration
- 9h 5m
- When
- Every day
- Estimated price
- $260–1,000
Flights from Indianapolis to José Joaquín De Olmedo International Airport via Fort Lauderdale
- Ave. Duration
- 9h 8m
- When
- Every day
- Estimated price
- $240–950
- Website
- aa.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 11h 25m
- When
- Every day
- Estimated price
- $200–750
Flights from Chicago Midway International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 10h 19m
- When
- Saturday
- Estimated price
- $260–950
Flights from Indianapolis to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 16h 39m
- When
- Every day
- Estimated price
- $240–950
- Website
- avianca.com
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Bogota
- Ave. Duration
- 9h 35m
- When
- Every day
- Estimated price
- $330–1,100
Flights from Chicago O'Hare International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 10h 21m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $320–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-589-6004
- [email protected]
- Website
- goexpresstravel.com
Shuttle from Holiday Inn City Centre to Indianapolis Airport
- Ave. Duration
- 1h 25m
- Frequency
- On demand
- Estimated price
- $33
- Schedules at
- goexpresstravel.com
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from Holiday Inn City Centre to Indianapolis Airport
- Ave. Duration
- 1h 49m
- Frequency
- Every 3 hours
- Estimated price
- $14–28
- Schedules at
- lafayettelimo.com
- Child
- $14–23
- Adult
- $24–28
- [email protected]
- Website
- reina-del-camino.com
Bus from Manta to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- https://www.facebook.com/ReinadelCaminoOficial
Want to know more about travelling around Ecuador
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide





