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How to get fromChicago to Harrisburgby train, taxi, bus, car, or plane

Find Transport to Harrisburg

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There are 8 ways to get from Chicago to Harrisburg by train, taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from Chicago Union Station to Carbondaletrain train Saluki / ...
    2. Take the taxi from Carbondale to Harrisburgtaxi taxi
    6h 20m
    $185–313

  2. Drive 309.5 mi

    cheapest
    1. Drive from Chicago to Harrisburgcar car 309.5 mi
    6h 28m
    $57–82

  3. Bus

    1. Take the bus from Chicago to Marathon Gas Station - Marionbus bus Chicago / ...
    8h 30m
    $80–204

  4. Fly to Williamson County Regional Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the bus from Marion, IL to Harrisburg, ILbus bus
    5h 1m
    $98–247

  5. Fly to Evansville, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Evansville (EVV)plane plane ORD - EVV
    2. Drive from Evansville (EVV) to Harrisburgcar car
    4h 42m
    $60–314

  6. Fly to Barkley Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Harrisburgtaxi taxi
    4h 27m
    $168–465

  7. Fly to Cape Girardeau Municipal Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    2. Drive from Cape Girardeau Municipal Airport (CGI) to Harrisburgcar car
    5h 11m
    $112–248

  8. Fly to Owensboro–Daviess County Regional Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Owensboro–Daviess County Regional Airport (OWB)plane plane ORD - OWB
    2. Drive from Owensboro–Daviess County Regional Airport (OWB) to Harrisburgcar car
    5h 11m
    $98–238

Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights

Calendar19Weekly Planes
Duration1h 31mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Harrisburg.ExpandLaunch map view
  • Distance: 346.9 mi
  • Duration: 6h 20m

What companies run services between Chicago, IL, USA and Harrisburg, IL, USA?

Tornado Bus Company operates a bus from Chicago to Marathon Gas Station - Marion once daily. Tickets cost $65–180 and the journey takes 5h 5m.

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