There are 6 ways to get from Chicago to Houston by train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain Empire Builder / ...
5h 34m$205–303Drive 301.5 mi
cheapest- Drive from Chicago to Houstoncar 301.5 mi
5h 3m$54–77Bus via Milwaukee
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus Greyhound US0150
- Take the bus from Milwaukee to La Crossebus Jefferson Lines 966
6h 51m$114–159Fly to La Crosse
- Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane ORD - LSE
3h 38m$92–325Bus
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus Van Galder
- Take the bus from Madison to La Crossebus Jefferson Lines 966
7h 31m$111–169Fly to Chippewa Valley Regional Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Chippewa Valley Regional Airport (EAU)plane ORD - EAU
- Drive from Eau-Claire-Airport-EAU to Houstoncar
5h 15m$54–290
Chicago O'Hare International Airport (ORD) to La Crosse (LSE) flights
Comparing Your Travel Options
The cheapest way to get from Chicago to Houston is to drive which costs $50 - $80 and takes 5h 3m.
The fastest way to get from Chicago to Houston is to fly which takes 3h 38m and costs $90 - $330.
No, there is no direct bus from Chicago station to Houston. However, there are services departing from Chicago Bus Station and arriving at La Crosse via Milwaukee. The journey, including transfers, takes approximately 6h 51m.
No, there is no direct train from Chicago station to Houston station. However, there are services departing from Chicago Union Station and arriving at La Crosse Amtrak Station via . The journey, including transfers, takes approximately 5h 34m.
The distance between Chicago and Houston is 304 miles. The road distance is 303.2 miles.
The best way to get from Chicago to Houston without a car is to train which takes 5h 34m and costs $200 - $310.
It takes approximately 5h 34m to get from Chicago to Houston, including transfers.
Chicago to Houston bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Houston train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Houston is to train which takes 5h 34m and costs $200 - $310. Alternatively, you can bus via Milwaukee, which costs $110 - $160 and takes 6h 51m, you could also fly, which costs $90 - $330 and takes 3h 38m.
What companies run services between Chicago, IL, USA and Houston, MN, USA?
Amtrak operates a train from Chicago Union Station to La Crosse Amtrak Station 3 times a day. Tickets cost $150–240 and the journey takes 4h 59m. Alternatively, you can take a bus from Chicago Bus Station to Houston via Milwaukee Intermodal Station, Milwaukee, and La Crosse in around 6h 51m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $35–250
- Website
- united.com
Flights from Chicago O'Hare International Airport to Chippewa Valley Regional Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $35–260
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Chicago to Houston bus services, operated by Greyhound USA, arrive at Milwaukee Intermodal Station.
Chicago to Houston train services, operated by Amtrak, arrive at La Crosse Amtrak Station.
Yes, the driving distance between Chicago to Houston is 303 miles. It takes approximately 5h 3m to drive from Chicago to Houston.
There are two+ hotels available in Houston.










