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How to get fromChicago to Houstonby train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus

Find Transport to Houston

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There are 6 ways to get from Chicago to Houston by train (Amtrak), bus (Greyhound, Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    5h 34m
    $205–303
  2. Drive  301.5 mi

    cheapest
    1. Drive from Chicago to Houstoncar car 301.5 mi
    5h 3m
    $54–77
  3. Bus via Milwaukee

    1. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150
    2. Take the bus from Milwaukee to La Crossebus bus Jefferson Lines 966
    6h 51m
    $114–159
  4. Fly to La Crosse

    1. Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane plane ORD - LSE
    3h 38m
    $92–325
  5. Bus

    1. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    2. Take the bus from Madison to La Crossebus bus Jefferson Lines 966
    7h 31m
    $111–169
  6. Fly to Chippewa Valley Regional Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Chippewa Valley Regional Airport (EAU)plane plane ORD - EAU
    2. Drive from Eau-Claire-Airport-EAU to Houstoncar car
    5h 15m
    $54–290

Chicago O'Hare International Airport (ORD) to La Crosse (LSE) flights

Calendar21Weekly Planes
Duration1h 22mAverage Duration
Ticket$36Cheapest Price
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Comparing Your Travel Options

What companies run services between Chicago, IL, USA and Houston, MN, USA?

Amtrak operates a train from Chicago Union Station to La Crosse Amtrak Station 3 times a day. Tickets cost $150–240 and the journey takes 4h 59m. Alternatively, you can take a bus from Chicago Bus Station to Houston via Milwaukee Intermodal Station, Milwaukee, and La Crosse in around 6h 51m.

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