There are 6 ways to get from Chicago to Isle of Palms by plane, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Chicago Midway International Airport
best- Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane MDW - CHS
4h 6m$192–665Drive 879.7 mi
cheapest- Drive from Chicago to Isle of Palmscar 879.7 mi
16h 9m$161–232Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus Greyhound US0100
- Take the bus from Atlanta Bus Station to Charleston Bus Stationbus Greyhound US0641S
28h 49m$239–420Train via Petersburg (Amtrak)
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain Floridian
- Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain Silver Meteor / ...
28h 50m$459–911Fly from Chicago O'Hare International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane ORD - CHS
4h 33m$172–525Train (Amtrak)
- Take the train from Chicago Union Station to Savannah Stationtrain Floridian
- Take the train from Savannah Station to Charleston Amtrak Stationtrain Palmetto / ...
34h 35m$540–1,072
Chicago Midway International Airport (MDW) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Chicago to Isle of Palms is to drive which costs $160 - $240 and takes 16h 9m.
The fastest way to get from Chicago to Isle of Palms is to fly which takes 4h 6m and costs $190 - $700.
No, there is no direct bus from Chicago station to Isle of Palms station. However, there are services departing from Chicago Bus Station and arriving at Charleston Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 28h 49m.
No, there is no direct train from Chicago station to Isle of Palms station. However, there are services departing from Chicago Union Station and arriving at Charleston Amtrak Station via Petersburg Amtrak Station. The journey, including transfers, takes approximately 28h 50m.
The distance between Chicago and Isle of Palms is 783 miles. The road distance is 884.9 miles.
The best way to get from Chicago to Isle of Palms without a car is to bus which takes 28h 49m and costs $230 - $420.
It takes approximately 4h 6m to get from Chicago to Isle of Palms, including transfers.
Chicago to Isle of Palms bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Isle of Palms train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Isle of Palms is to fly which takes 4h 6m and costs $190 - $700. Alternatively, you can bus, which costs $230 - $420 and takes 28h 49m, you could also train via Petersburg, which costs $450 - $950 and takes 28h 50m.
What companies run services between Chicago, IL, USA and Isle of Palms, SC, USA?
Southwest Airlines and Delta fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Isle of Palms via Atlanta Bus Station and Charleston Bus Station in around 28h 49m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Charleston International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago Midway International Airport to Charleston International Airport via Nashville
- Ave. Duration
- 4h 27m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $100–550
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Charleston International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $80–410
Flights from Chicago O'Hare International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $80–410
- Website
- united.com
Flights from Chicago O'Hare International Airport to Charleston International Airport
- Ave. Duration
- 2h 26m
- When
- Every day
- Estimated price
- $80–410
- Website
- delta.com
Flights from Chicago Midway International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $280–600
- Website
- Amtrak
Train from Petersburg Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $110–240
- Website
- Amtrak
Train from Chicago Union Station to Savannah Station
- Ave. Duration
- 31h 38m
- Frequency
- Once daily
- Estimated price
- $450–950
- Website
- Amtrak
Train from Savannah Station to Charleston Amtrak Station
- Ave. Duration
- 1h 33m
- Frequency
- Twice daily
- Estimated price
- $30–70
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- Every 4 hours
- Estimated price
- $100–210
- Website
- Greyhound
Bus from Atlanta Bus Station to Charleston Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Twice daily
- Estimated price
- $70–140
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 40m
- Frequency
- 3 times a day
- Estimated price
- $110–190
- Schedules at
- Flixbus USA
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More Questions & Answers
Chicago to Isle of Palms bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Isle of Palms is 1h ahead of Chicago. It is currently 12:41 AM in Chicago and 1:41 AM in Isle of Palms.
Chicago to Isle of Palms train services, operated by Amtrak, arrive at Petersburg Amtrak Station.
Yes, the driving distance between Chicago to Isle of Palms is 885 miles. It takes approximately 16h 9m to drive from Chicago to Isle of Palms.
There are 1496+ hotels available in Isle of Palms.






