There are 6 ways to get from Chicago to Jefferson City by plane, train (Amtrak), bus (Flixbus, Greyhound), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Columbia Regional Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 39m$138–415Drive 389.9 mi
cheapest- Drive from Chicago to Jefferson Citycar 389.9 mi
6h 55m$72–103Train (Amtrak)
- Take the train from Chicago Union Station to Jefferson City Stationtrain Lincoln Service Missouri River Runner
7h 46m$130–270Bus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
- Take the bus from St Louis Bus Station to Jefferson Citybus Greyhound US0175s
11h 3m$87–149Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, shuttle
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
- Take a shuttle bus from St Louis International Airport to Jefferson City, Missouri
6h$408–855Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, shuttle
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
- Take a shuttle bus from St Louis International Airport to Jefferson City, Missouri
5h 44m$218–705
Chicago to Jefferson City by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Jefferson City is to drive which costs $70 - $110 and takes 6h 55m.
The fastest way to get from Chicago to Jefferson City is to fly which takes 3h 39m and costs $130 - $420.
No, there is no direct bus from Chicago station to Jefferson City. However, there are services departing from Chicago Bus Station and arriving at Jefferson City via St Louis Bus Station. The journey, including transfers, takes approximately 11h 3m.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Jefferson City Station station. Services depart once daily, and operate every day. The journey takes approximately 7h 46m.
The distance between Chicago and Jefferson City is 357 miles. The road distance is 392.2 miles.
The best way to get from Chicago to Jefferson City without a car is to train which takes 7h 46m and costs $130 - $270.
It takes approximately 3h 39m to get from Chicago to Jefferson City, including transfers.
Chicago to Jefferson City bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Jefferson City train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Jefferson City is to fly which takes 3h 39m and costs $130 - $420. Alternatively, you can train, which costs $130 - $270 and takes 7h 46m, you could also bus, which costs $85 - $150 and takes 11h 3m.
What companies run services between Chicago, IL, USA and Jefferson City, MO, USA?
American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU) every 4 hours. Alternatively, Amtrak operates a train from Chicago Union Station to Jefferson City Station once daily. Tickets cost $130–270 and the journey takes 7h 46m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $80–550
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $45–300
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $60–410
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–300
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $60–410
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Jefferson City Station
- Ave. Duration
- 7h 46m
- Frequency
- Once daily
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Jefferson City
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
- Phone
- 573-368-4656
- [email protected]
- Website
- usaxonline.com
Shuttle from St Louis International Airport to Jefferson City, Missouri
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $135–150
- Website
- https://usaxonline.com/
Shuttle from St Louis International Airport to Jefferson City, Missouri
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $135–150
- Website
- https://usaxonline.com/
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More Questions & Answers
Chicago to Jefferson City bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Jefferson City train services, operated by Amtrak, arrive at Jefferson City Station.
Yes, the driving distance between Chicago to Jefferson City is 392 miles. It takes approximately 6h 55m to drive from Chicago to Jefferson City.
Book your Chicago to Jefferson City train tickets online with Omio.
Book your Chicago to Jefferson City bus tickets online with Omio.
There are 19+ hotels available in Jefferson City.