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How to get fromChicago to Jefferson Cityby plane, taxi, bus (Greyhound, Flixbus), car, bus (Flixbus, Greyhound), train, or bus

Find Transport to Jefferson City

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There are 10 ways to get from Chicago to Jefferson City by plane, taxi, bus (Greyhound, Flixbus), car, bus (Flixbus, Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Mcghee Tyson Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    2. Take the taxi from Mcghee Tyson Airport (TYS) to Jefferson Citytaxi taxi
    4h 26m
    $292–875

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Jefferson Citycar car
    5h 31m
    $80–371

  3. Bus

    1. Take the bus from Chicago Bus Station to Nashville Bus Stationbus bus Greyhound US0100
    2. Take the bus from Nashville Bus Station to Knoxville Area Transit Bus Stopbus bus Greyhound US0600
    14h 43m
    $198–319

  4. Drive 536.6 mi

    1. Drive from Chicago to Jefferson Citycar car 536.6 mi
    10h 13m
    $98–142

  5. Fly Chicago O'Hare International Airport to Tri-Cities Regional Tn/Va Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Jefferson Citycar car
    4h 51m
    $86–435

  6. Fly Chicago Midway International Airport to Mcghee Tyson Airport, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    2. Take the taxi from Mcghee Tyson Airport (TYS) to Jefferson Citytaxi taxi
    3h 56m
    $312–1,025

  7. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Jefferson Citycar car
    6h 42m
    $120–595

  8. Bus via Dayton

    1. Take the bus from Chicago Bus Station to Dayton Trotwood Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Dayton Trotwood Bus Station to Knoxville Area Transit Bus Stopbus bus Greyhound US0110
    14h 58m
    $173–290

  9. Train, bus

    1. Take the train from Chicago Union Station to Carbondaletrain train
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Knoxville Area Transit Bus Stopbus bus
    15h 13m
    $254–443

  10. Train, bus via Reading

    1. Take the train from Chicago Union Station to Indianapolistrain train
    2. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus
    3. Take the bus from Cincinnati Bus Station to Knoxville Area Transit Bus Stopbus bus
    16h 17m
    $215–388

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar72Weekly Planes
Duration2h 46mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Jefferson City.ExpandLaunch map view
  • Distance: 534.5 mi
  • Duration: 4h 26m

What companies run services between Chicago, IL, USA and Jefferson City, TN, USA?

You can take a bus from Chicago Bus Station to Jefferson City via Nashville Bus Station and Knoxville Area Transit Bus Stop in around 14h 43m.

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