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How to get fromChicago to Jeffersonby plane, shuttle, taxi, bus, car, or train

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There are 11 ways to get from Chicago to Jefferson by plane, shuttle, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Tri-Cities Regional Tn/Va Airport, shuttle, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane ORD - TRI
    2. Take a shuttle bus from Black Bear Resort to Americourt Hotel - Mountain Cityshuttle bus
    3. Take the taxi from Americourt Hotel - Mountain City to Jeffersontaxi taxi
    6h 39m
    $230–613

  2. Bus, drive

    cheapest
    1. Take the bus from Chicago to Columbus - Mound Stbus bus
    2. Take the bus from Columbus - Mound St to Wythevillebus bus
    3. Drive from Wytheville to Jeffersoncar car
    17h 54m
    $74–168

  3. Bus, drive via Columbus

    1. Take the bus from Chicago Bus Station to Columbusbus bus
    2. Take the bus from Columbus - Mound St to Wythevillebus bus
    3. Drive from Wytheville to Jeffersoncar car
    17h 48m
    $102–192

  4. Train, bus, drive

    1. Take the train from Chicago Union Station to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland to Wythevillebus bus
    3. Drive from Wytheville to Jeffersoncar car
    19h 9m
    $180–384

  5. Drive 625.9 mi

    1. Drive from Chicago to Jeffersoncar car 625.9 mi
    12h 9m
    $115–165

  6. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take the taxi from ASU Peacock Hall Boone to Jeffersontaxi taxi
    7h 52m
    $272–600

  7. Fly Chicago O'Hare International Airport to Mcghee Tyson Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Jeffersoncar car
    7h 5m
    $132–655

  8. Fly Chicago O'Hare International Airport to Asheville Regional Airport, shuttle, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take a shuttle bus from Asheville Airport to Black Bear Resortshuttle bus
    3. Take a shuttle bus from Black Bear Resort to Americourt Hotel - Mountain Cityshuttle bus
    4. Take the taxi from Americourt Hotel - Mountain City to Jeffersontaxi taxi
    8h 17m
    $316–613

  9. Fly Chicago Midway International Airport to Charlotte Douglas International Airport, bus, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    2. Take the bus from Charlotte Airport to ASU Peacock Hall Boonebus bus
    3. Take the taxi from ASU Peacock Hall Boone to Jeffersontaxi taxi
    7h 35m
    $272–890

  10. Fly Chicago O'Hare International Airport to Roanoke Regional Airport-Woodrum Field, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane ORD - ROA
    2. Take the bus from Airport to Exit 118 - Park and Ridebus bus
    3. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    4. Take the taxi from Wytheville Rural King Parking Lot to Jeffersontaxi taxi
    9h 3m
    $224–552

  11. Fly Chicago O'Hare International Airport to Piedmont Triad International Airport, bus, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    2. Take the bus from Winston Salem(Trans Center) to Wythevillebus bus
    3. Drive from Wytheville to Jeffersoncar car
    8h 51m
    $140–685

Chicago O'Hare International Airport (ORD) to Tri-Cities Regional Tn/Va Airport (TRI) flights

Calendar27Weekly Planes
Duration2h 57mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Jefferson.ExpandLaunch map view
  • Distance: 594.6 mi
  • Duration: 6h 39m

What companies run services between Chicago, IL, USA and Jefferson, NC, USA?

There is no direct connection from Chicago to Jefferson. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Tri-Cities Regional Tn/Va Airport (TRI), walk to Tri Cities Airport, take the shuttle to Black Bear Resort, take the shuttle to Americourt Hotel - Mountain City, then take the taxi to Jefferson. Alternatively, you can take a bus from Chicago Bus Station to Jefferson via Columbus, E Main St & S High St, S Grant Ave & E Mound St, Columbus - Mound St, and Wytheville in around 17h 48m.

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