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How to get fromChicago to Jeffersonvilleby plane, taxi, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Chicago to Jeffersonville by plane, taxi, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to John Glenn Columbus International Airport, taxi

    best
    1. Fly from Chicago Midway International Airport (MDW) to John Glenn Columbus International Airport (CMH)plane plane MDW - CMH
    2. Take the taxi from Columbus-Airport-CMH to Jeffersonvilletaxi taxi
    3h 35m
    $202–705

  2. Drive 324.1 mi

    cheapest
    1. Drive from Chicago to Jeffersonvillecar car 324.1 mi
    6h 2m
    $60–86

  3. Bus via Indianapolis (Greyhound)

    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Springfieldbus bus Greyhound US0421
    7h 25m
    $102–161

  4. Train, bus

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Springfieldbus bus Greyhound US0421
    9h 14m
    $135–236

  5. Fly Chicago O'Hare International Airport to John Glenn Columbus International Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to John Glenn Columbus International Airport (CMH)plane plane ORD - CMH
    2. Take the taxi from Columbus-Airport-CMH to Jeffersonvilletaxi taxi
    4h 5m
    $672–1,055

  6. Fly Chicago O'Hare International Airport to Dayton, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Dayton (DAY)plane plane ORD - DAY
    2. Take the taxi from Dayton-Airport-DAY to Jeffersonvilletaxi taxi
    4h 17m
    $162–435

  7. Bus

    1. Take the bus from Chicago Bus Station to Dayton Trotwood Bus Stationbus bus FlixBus 2511 / ...
    2. Take the bus from Dayton Trotwood Bus Station to Springfieldbus bus Greyhound US0105 / ...
    7h 55m
    $88–150

Chicago Midway International Airport (MDW) to John Glenn Columbus International Airport (CMH) flights

Calendar27Weekly Planes
Duration1h 14mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Jeffersonville.ExpandLaunch map view
  • Distance: 341.1 mi
  • Duration: 3h 35m

What companies run services between Chicago, IL, USA and Jeffersonville, OH, USA?

You can take a bus from Chicago Bus Station to Jeffersonville via Indianapolis Union Station and Springfield in around 7h 25m.

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