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How to get fromChicago to Key Largoby plane, shuttle, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 10 ways to get from Chicago to Key Largo by plane, shuttle, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Miami International Airport, shuttle

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Miami International Airport (MIA)plane plane ORD - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 15m
    $272–835

  2. Fly Chicago O'Hare International Airport to Key West International Airport, bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)plane plane ORD - EYW
    2. Take the bus from Key West Airport to Key Largo Bus Stopbus bus
    9h
    $90–391

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    32h 55m
    $203–396

  4. Train, bus

    1. Take the train from Chicago Union Station to Hollywood Amtrak Stationtrain train Floridian
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    2d 1h
    $562–1,230

  5. Drive 1,369.5 mi

    1. Drive from Chicago to Key Largocar car 1,369.5 mi
    24h 51m
    $250–361

  6. Fly Chicago Midway International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Chicago Midway International Airport (MDW) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MDW - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 9m
    $272–525

  7. Fly Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Chicago O'Hare International Airport (ORD) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane ORD - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 37m
    $302–625

  8. Fly Chicago Midway International Airport to Miami International Airport, shuttle

    1. Fly from Chicago Midway International Airport (MDW) to Miami International Airport (MIA)plane plane MDW - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    6h 49m
    $232–785

  9. Fly Chicago O'Hare International Airport to President Donald J. Trump International Airport, train, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to President Donald J. Trump International Airport (PBI)plane plane ORD - PBI
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    10h 45m
    $118–534

  10. Bus via Pembroke Pines (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Hollywood Sheridan Trirail Stationbus bus
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    37h 11m
    $202–392

Chicago to Key Largo by bus

Calendar14Weekly Buses
Duration32h 55mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Key Largo.ExpandLaunch map view
  • Distance: 1,274.2 mi
  • Duration: 7h 15m

What companies run services between Chicago, IL, USA and Key Largo, FL, USA?

You can take a bus from Chicago Bus Station to Key Largo Bus Stop via Atlanta Bus Station and Miami Airport Station in around 32h 55m.

Airlines
Train operators
Bus operators

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