There are 5 ways to get from Chicago to Kirksville by train (Amtrak), car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Chicago Union Station to La Plata Stationtrain Southwest Chief
5h 9m$142–249Drive 346.5 mi
cheapest- Drive from Chicago to Kirksvillecar 346.5 mi
7h 19m$64–92Fly to Kirksville Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)plane ORD - IRK
3h 28m$102–240Fly to Columbia Regional Airport, shuttle
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
5h 59m$102–376Fly to Burlington Municipal Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane ORD - BRL
- Drive from Burlington Municipal Airport (BRL) to Kirksvillecar
5h 55m$78–170
Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK) flights
Questions & Answers
The cheapest way to get from Chicago to Kirksville is to drive which costs $60 - $95 and takes 7h 19m.
The fastest way to get from Chicago to Kirksville is to fly which takes 3h 28m and costs $100 - $240.
No, there is no direct train from Chicago station to Kirksville station. However, there are services departing from Chicago Union Station and arriving at La Plata Station via . The journey, including transfers, takes approximately 5h 9m.
The distance between Chicago and Kirksville is 312 miles. The road distance is 348.5 miles.
The best way to get from Chicago to Kirksville without a car is to train which takes 5h 9m and costs $140 - $250.
It takes approximately 5h 9m to get from Chicago to Kirksville, including transfers.
Chicago to Kirksville train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Kirksville is to train which takes 5h 9m and costs $140 - $250. Alternatively, you can fly, which costs $100 - $240 and takes 3h 28m.
Chicago to Kirksville train services, operated by Amtrak, arrive at La Plata Station.
Yes, the driving distance between Chicago to Kirksville is 349 miles. It takes approximately 7h 19m to drive from Chicago to Kirksville.
What companies run services between Chicago, IL, USA and Kirksville, MO, USA?
Amtrak operates a train from Chicago Union Station to La Plata Station once daily. Tickets cost $95–200 and the journey takes 4h 52m. Alternatively, Corporate Flight Management Inc flies from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK) once daily.
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Kirksville Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–190
Flights from Chicago O'Hare International Airport to Burlington Municipal Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–130
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–300
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $45–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to La Plata Station
- Ave. Duration
- 4h 52m
- Frequency
- Once daily
- Estimated price
- $95–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
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More Questions & Answers
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